Cold Spring Harbor Library  CSHL: Home
   Home       Services       Archives       About Us   
 
CSHL Publication List
CSHL Authors Publications
Go back to Search Mode

          
Sort by   in order
126 Article(s) on File
Page 1 of 1
Missing-in-Metastasis regulates cell motility and invasion via PTPdelta-mediated changes in SRC activity
Chaudhary F,
Lucito R,
Tonks NK

Biochemical Journal
  (0): Oct 7 2014   Nlm
[Abstract]
[DOI] [Full Text]

Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence
Yang M,
Haase AD,
Huang FK,
Coulis G,
Rivera KD,
Dickinson BC,
Chang CJ,
Pappin DJ,
Neubert TA,
Hannon GJ,
Boivin B,
Tonks NK

Molecular Cell
  55 (5): 782-790; Aug 27 2014   Nlm
[Abstract]
[DOI] [Full Text]

Reactivation of oxidized PTP1B and PTEN by Thioredoxin 1
Schwertassek U,
Haque A,
Krishnan N,
Greiner R,
Weingarten L,
Dick TP,
Tonks NK

Febs Journal
  281 (16): 3545-3558; Aug 2014   Nlm
[Abstract]
[DOI] [Full Text]

Targeting the disordered C terminus of PTP1B with an allosteric inhibitor
Krishnan N,
Koveal D,
Miller DH,
Xue B,
Akshinthala SD,
Kragelj J,
Jensen MR,
Gauss CM,
Page R,
Blackledge M,
Muthuswamy SK,
Peti W,
Tonks NK

Nature Chemical Biology
  10 (7): 558-566; Jul 2014   NLM
[DOI] [Full Text]

A Unified Nomenclature and Amino Acid Numbering for Human PTEN
Pulido R,
Baker SJ,
Barata JT,
Carracedo A,
Cid VJ,
Chin-Sang ID,
Dave V,
den Hertog J,
Devreotes P,
Eickholt BJ,
Eng C,
Furnari FB,
Georgescu MM,
Gericke A,
Hopkins B,
Jiang X,
Lee SR,
Losche M,
Malaney P,
Matias-Guiu X,
Molina M,
Pandolfi PP,
Parsons R,
Pinton P,
Rivas C,
Rocha RM,
Rodriguez MS,
Ross AH,
Serrano M,
Stambolic V,
Stiles B,
Suzuki A,
Tan SS,
Tonks NK,
Trotman LC,
Wolff N,
Woscholski R,
Wu H,
Leslie NR

Science signaling
  7 (332): pe15; Jul 1 2014   Nlm
[Abstract]
[DOI] [Full Text]

Nox4 redox regulation of PTP1B contributes to the proliferation and migration of glioblastoma cells by modulating tyrosine phosphorylation of coronin-1C
Mondol AS,
Tonks NK,
Kamata T

Free Radical Biology and Medicine
  67 (0): 285-91; Feb 2014   Nlm
[Abstract]
[DOI] [Full Text]

Receptor protein-tyrosine phosphatase α regulates focal adhesion kinase phosphorylation and ErbB2 oncoproteinmediated mammary epithelial cell motility
Boivin B,
Chaudhary F,
Dickinson BC,
Haque A,
Pero SC,
Chang CJ,
Tonks NK

Journal of Biological Chemistry
  288 (52): 36926-36935; Nov 2013  
[Abstract]
[DOI] [Full Text]

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-ß receptor tyrosine kinase signaling
Dagnell M,
Frijhoff J,
Pader I,
Augsten M,
Boivin B,
Xu J,
Mandal PK,
Tonks NK,
Hellberg C,
Conrad M,
Arnér ES,
Östman A

Proceedings of the National Academy of Sciences of the United States of America
  110 (33): 13398-13403; Aug 13 2013  
[Abstract]
[DOI] [Full Text]

Protein Tyrosine Phosphatase 1B Antagonized Signaling by IGF-1 Receptor and BRK/PTK6 in Ovarian Cancer Cells
Fan G,
Lin G,
Lucito R,
Tonks NK

J Biol Chem
  288 (34): 24923-24934; Aug 2013   NLM
[Abstract]
[DOI] [Full Text]

The anti-inflammatory compound BAY 11-7082 is a potent inhibitor of Protein Tyrosine Phosphatases
Krishnan N,
Bencze G,
Cohen P,
Tonks NK

FEBS J
  280 (12): 2830-2841; JUn 2013   NLM
[Abstract]
[DOI] [Full Text]

Protein Tyrosine Phosphatases: Critical Regulators of Signaling in Cancer
Tonks NK

Faseb Journal
  27 (0): Apr 27 2013  
[Abstract]
[Full Text]

Proteomic identification of carboplatin resistance in ovarian cancer cells
Wrzeszczynski KO,
Fan GF,
Fu CX,
Pappin DJ,
Lucito R,
Tonks NK

Cancer Research
  73 (8): 2502; Apr 2013  
[Abstract]
[DOI] [Full Text]

Binge Drinking Induces Whole-Body Insulin Resistance by Impairing Hypothalamic Insulin Action
Lindtner C,
Scherer T,
Zielinski E,
Filatova N,
Fasshauer M,
Tonks NK,
Puchowicz M,
Buettner C

Science Translational Medicine
  5 (170): Jan 30 2013  
[Abstract]
[DOI] [Full Text]

Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction
Tonks NK

Febs Journal
  280 (2): 346-378; Jan 17 2013  
[Abstract]
[DOI] [Full Text]

Special Issue: Protein Phosphatases: From Molecules to Networks Introduction
Tonks NK

FEBS J
  (0): Dec 24 2012   NLM
[Abstract]
[DOI] [Full Text]

The use of phage display to generate conformation-sensor recombinant antibodies
Haque A,
Tonks NK

Nat Protoc
  7 (12): 2127-43; Nov 15 2012   NLM
[Abstract]
[DOI] [Full Text]

Harnessing Redox Regulation Of Protein Tyrosine Phosphotases
Tonks NK

Free Radical Biology and Medicine
  53 (0): S3-S3; Nov 1 2012  
[DOI] [Full Text]

Expression profiling during mammary epithelial cell 3D morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2 mediated transformation
Yu M,
Lin G,
Arshadi N,
Kalatskaya I,
Xue B,
Haider S,
Nguyen F,
Boutros PC,
Elson A,
Muthuswamy LB,
Tonks NK,
Muthuswamy SK

Mol Cell Biol
  32 (19): 3913-3924; Oct 2012   NLM
[Abstract]
[DOI] [Full Text]

Functional analysis of the protein phosphatase activity of PTEN
Zhang XC,
Piccini A,
Myers MP,
Van Aelst L,
Tonks NK

Biochem J
  444 (3): 457-64; Jun 15 2012   NLM
[Abstract]
[DOI] [Full Text]

H(2)S-Induced Sulfhydration of the Phosphatase PTP1B and Its Role in the Endoplasmic Reticulum Stress Response
Krishnan N,
Fu CX,
Pappin DJ,
Tonks NK

Science Signaling
  4 (203): Dec 2011  
[Abstract]
[DOI] [Full Text]

Conformation-Sensing Antibodies Stabilize the Oxidized Form of PTP1B and Inhibit Its Phosphatase Activity
Haque A,
Andersen J,
Salmeen A,
Barford D,
Tonks NK

Cell
  147 (1): 185-198; Sep 30 2011  
[Abstract]
[DOI] [Full Text]

Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the PTP-ome
Lin G,
Aranda V,
Muthuswamy SK,
Tonks NK

Genes Development
  25 (13): 1412-1425; Jul 2011   PMC3134084
[Abstract]
[DOI]

Diverse injurious stimuli reduce protein tyrosine phosphatase-μ expression and enhance epidermal growth factor receptor signaling in human airway epithelia
Hyun SW,
Anglin IE,
Liu A,
Yang S,
Sorkin JD,
Lillehoj E,
Tonks NK,
Passaniti A,
Goldblum SE

Experimental Lung Research
  37 (6): 327-343; 2011  
[Abstract]
[DOI]

Targeting the reversibly oxidized protein tyrosine phosphatase superfamily
Boivin B,
Tonks NK,
Yang M

Science Signaling
  3 (137): Aug 31 2010  
[Abstract]
[DOI] [Full Text]

Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis
Schwertassek U,
Buckley DA,
Xu CF,
Lindsay AJ,
McCaffrey MW,
Neubert TA,
Tonks NK

Febs Journal
  277 (11): 2463-2473; Jun 2010   PMCID: PMC2894504
[Abstract]
[DOI] [Full Text] [PDF]

The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation
Hinton SD,
Myers MP,
Roggero VR,
Allison LA,
Tonks NK

Biochemical Journal
  427 (0): 349-357; May 1 2010   PMCID: PMC2873733
[Abstract]
[DOI] [Full Text] [PDF]

Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
Jung SK,
Jeong DG,
Chung SJ,
Kim JH,
Park BC,
Tonks NK,
Ryu SE,
Kim SJ

FASEB J.
  24 (2): 560-569; Feb 2010  
[Abstract]
[DOI] [Full Text] [PDF]

Analysis of the redox regulation of protein tyrosine phosphatase superfamily members utilizing a cysteinyl-labeling assay
Boivin B,
Tonks NK

Methods Enzymol
  474 (0): 35-50; 2010  
[Abstract]
[DOI] [Full Text] [PDF]

Pseudophosphatases: grab and hold on
Tonks NK

Cell
  139 (3): 464-5; Oct 30 2009  
[Abstract]
[DOI] [Full Text] [PDF]

Reactive Oxygen Species Enhance Insulin Sensitivity
Loh K,
Deng H,
Fukushima A,
Cai X,
Boivin B,
Galic S,
Bruce C,
Shields BJ,
Skiba B,
Ooms LM,
Stepto N,
Wu B,
Mitchell CA,
Tonks NK,
Watt MJ,
Febbraio MA,
Crack PJ,
Andrikopoulos S,
Tiganis T

Cell Metabolism
  10 (4): 260-272; Oct 7 2009   PMCID: PMC2892288
[Abstract]
[DOI] [Full Text] [PDF]

Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent
Krishnan N,
Jeong DG,
Jung S,
Ryu SE,
Xiao A,
Allis CD,
Kim SJ,
Tonks NK

Journal of Biological Chemistry
  284 (24): 16066-16070; Jun 12 2009   PMCID: PMC2713548
[Abstract]
[DOI] [Full Text] [PDF]

Targeting the Kinome II
Hemmings BA,
Restuccia D,
Tonks NK

Curr Opin Cell Biol
  21 (2): 135-139; Apr 2009  
[DOI] [Full Text] [PDF]

A modified cysteinyl-labeling assay reveals reversible oxidation of classical and dual specificity phosphatases in angiomyolipoma cells
Boivin B,
Zhang SH,
Arbiser JL,
Zhang Z,
Tonks NK

Proc Natl Acad Sci U S A
  105 (29): 9959-9964; Jul 22 2008   PMCID: PMC2481340
[Abstract]
[DOI] [Full Text] [PDF]

Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR
Tabet F,
Schiffrin EL,
Callera G,
He Y,
Yao G,
Ostman A,
Kappert K,
Tonks NK,
Touyz RM

Circ Res
  103 (2): 149-158; Jul 18 2008   PMCID: PMC2758103
[Abstract]
[DOI] [Full Text] [PDF]

Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling
Juarez JC,
Manuia M,
Burnett ME,
Betancourt O,
Boivin B,
Shaw DE,
Tonks NK,
Mazar AP,
Donate F

Proc Natl Acad Sci U S A
  105 (20): 7147-7152; May 2008   PMCID: PMC2438219
[Abstract]
[DOI] [Full Text] [PDF]

Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells
Lou Y,
Chen Y,
Hsu S,
Chen R,
Lee C,
Khoo K,
Tonks NK,
Meng T

FEBS Journal
  275 (1): 69-88; Jan 2008  
[Abstract]
[DOI] [Full Text] [PDF]

The protein tyrosine phosphatase superfamily of enzymes
Tonks NK

Toxicology Letters
  172 (0): S10-S11; Oct 2007  
[DOI] [Full Text]

A Brake Becomes an Accelerator: PTP1B-A New Therapeutic Target for Breast Cancer
Tonks NK,
Muthuswamy SK

Cancer Cell
  11 (3): 214-6; Mar 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Protein tyrosine phosphatases: from genes, to function, to disease
Tonks NK

Nat Rev Mol Cell Biol
  7 (11): 833-46; Nov 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Redox redux: revisiting PTPs and the control of cell signaling
Tonks NK

Cell
  121 (5): 667-70; Jun 3 2005  
[Abstract]
[DOI] [Full Text]

Receptor protein tyrosine phosphatase mu regulates the paracellular pathway in human lung microvascular endothelia
Sui XF,
Kiser TD,
Hyun SW,
Angelini DJ,
Del Vecchio RL,
Young BA,
Hasday JD,
Romer LH,
Passaniti A,
Tonks NK,
Goldblum SE

American Journal of Pathology
  166 (4): 1247-1258; Apr 2005  
[Abstract]
[Full Text]

Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP
Galic S,
Hauser C,
Kahn BB,
Haj FG,
Neel BG,
Tonks NK,
Tiganis T

Molecular and Cellular Biology
  25 (2): 819-829; Jan 2005  
[Abstract]
[DOI] [Full Text] [PDF]

Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo
Meng TC,
Hsu SF,
Tonks NK

Methods
  35 (1): 28-36; Jan 2005  
[Abstract]
[Full Text]

Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2
Chen HH,
Luche R,
Wei B,
Tonks NK

J Biol Chem
  279 (40): 41404-13; Oct 1 2004  
[Abstract]
[DOI]

Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B
Meng TC,
Buckley DA,
Galic S,
Tiganis T,
Tonks NK

J Biol Chem
  279 (36): 37716-25; Sep 3 2004  
[Abstract]
[DOI]

The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis
Bukczynska P,
Klingler-Hoffmann M,
Mitchelhill KI,
Lam MH,
Ciccomancini M,
Tonks NK,
Sarcevic B,
Kemp BE,
Tiganis T

Biochemical Journal
  380 (0): 939-949; Jun 2004  
[Abstract]
[Full Text]

Protein tyrosine phosphatase-based therapeutics- lessons from PTP1B
Andersen JN,
Tonks NK
In:
Protein phosphatases
(eds. Ariño, J. Aslxander, D. R.) Berlin: Springer-Verlag; 2004. 5: 201-230  


A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage
Andersen JN,
Jansen PG,
Echwald SM,
Mortensen OH,
Fukada T,
Del Vecchio R,
Tonks NK,
Moller NP

FASEB J
  18 (1): 8-30; Jan 2004  
[Abstract]
[DOI] [Full Text]

Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3 - Implications for the control of protein stability and PTEN-protein interactions
Torres J,
Rodriguez J,
Myers MP,
Valiente M,
Graves JD,
Tonks NK,
Pulido R

Journal of Biological Chemistry
  278 (33): 30652-30660; Aug 2003  
[Abstract]
[Full Text]

PTP1B: From the sidelines to the front lines!
Tonks NK

Febs Letters
  546 (1): 140-148; Jul 2003  
[Abstract]
[Full Text]

The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase
Gray CH,
Good VM,
Tonks NK,
Barford D

Embo Journal
  22 (14): 3524-3535; Jul 2003  
[Abstract]
[Full Text]

Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate
Salmeen A,
Andersen JN,
Myers MP,
Meng TC,
Hinks JA,
Tonks NK,
Barford D

Nature
  423 (6941): 769-773; Jun 2003  
[Abstract]
[Full Text]

Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP
Galic S,
Klingler-Hoffmann M,
Fodero-Tavoletti MT,
Puryer MA,
Meng TC,
Tonks NK,
Tiganis T

Molecular and Cellular Biology
  23 (6): 2096-2108; Mar 2003  
[Abstract]
[Full Text]

Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1
Palka HL,
Park M,
Tonks NK

J Biol Chem
  278 (8): 5728-35; Feb 21 2003  
[Abstract]
[DOI]

Identification of YB-1 as a regulator of PTP1B expression: implications for regulation of insulin and cytokine signaling
Fukada T,
Tonks NK

Embo Journal
  22 (3): 479-493; Feb 2003  
[Abstract]
[Full Text]

Analysis of the regulation of protein tyrosine phosphatases in vivo by reversible oxidation
Meng TC,
Tonks NK
In:
Protein Phosphatases
(eds. ) San Diego: Academic Press Inc; 2003. 366: 304-+  
[Full Text]

in vivo by reversible oxidation CHAP=23Analysis of the Regulation of Protein Tyrosine Phosphatases in Vivo by Reversible Oxidation
Meng TC,
Tonks NK
In:
Protein Phosphatases
(eds. ) : ; 2003. 366: 304-18  
[DOI] [Full Text]

The C-elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis
Harrington RJ,
Gutch MJ,
Hengartner MO,
Tonks NK,
Chisholm AD

Development
  129 (9): 2141-2153; May 2002  
[Full Text]

PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy
Mayo LD,
Dixon JE,
Durden DL,
Tonks NK,
Donner DB

Journal of Biological Chemistry
  277 (7): 5484-5489; Feb 2002  
[Full Text]

Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo
Meng TC,
Fukada T,
Tonks NK

Molecular Cell
  9 (2): 387-399; Feb 2002  
[Full Text]

TYK2 and JAR2 are substrates of protein-tyrosine phosphatase 1B
Myers MP,
Andersen JN,
Cheng A,
Tremblay ML,
Horvath CM,
Parisien JP,
Salmeen A,
Barford D,
Tonks NK

Journal of Biological Chemistry
  276 (51): 47771-47774; Dec 2001  
[Abstract]
[DOI] [Full Text]

Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1
Shen Y,
Luche R,
Wei B,
Gordon ML,
Diltz CD,
Tonks NK

Proceedings of the National Academy of Sciences of the United States of America
  98 (24): 13613-13618; Nov 2001  
[Abstract]
[DOI] [Full Text]

PTP mu regulates the tyrosine phosphorylation state of VE-cadherin and the pulmonary microvascular endothelial paracellular pathway
Sui X,
Kiser TD,
DelVecchio RL,
Young BA,
Gregoryev D,
Garcia JG,
Tonks NK,
Goldblum SE

Molecular Biology of the Cell
  12 (0): 158A-158A; Nov 2001  
[Full Text]

Structural and evolutionary relationships among protein tyrosine phosphatase domains
Andersen JN,
Mortensen OH,
Peters GH,
Drake PG,
Iversen LF,
Olsen OH,
Jansen PG,
Andersen HS,
Tonks NK,
Moller NP

Molecular and Cellular Biology
  21 (21): 7117-7136; Nov 2001  
[Full Text]

Cellular stress regulates the nucleocytoplasmic distribution of the protein-tyrosine phosphatase TCPTP
Lam MH,
Michell BJ,
Fodero-Tavoletti MT,
Kemp BE,
Tonks NK,
Tiganis T

Journal of Biological Chemistry
  276 (40): 37700-37707; Oct 2001  
[Abstract]
[Full Text]

Crystal structure of the M-fragment of alpha-catenin: implications for modulation of cell adhesion
Yang J,
Dokurno P,
Tonks NK,
Barford D

Embo Journal
  20 (14): 3645-3656; Jul 2001  
[Abstract]
[Full Text]

The reciprocal role of Egr-1 and Sp family proteins in regulation of the PTP1B promoter in response to the p210 Bcr-Abl oncoprotein-tyrosine kinase
Fukada T,
Tonks NK

Journal of Biological Chemistry
  276 (27): 25512-25519; Jul 2001  
[Abstract]
[DOI] [Full Text]

Combinatorial control of the specificity of protein tyrosine phosphatases
Tonks NK,
Neel BG

Current Opinion in Cell Biology
  13 (2): 182-195; Apr 2001  
[Abstract]
[DOI] [Full Text]

PTEN controls tumor-induced angiogenesis
Wen SH,
Stolarov J,
Myers MP,
Su JD,
Wigler MH,
Tonks NK,
Durden DL

Proceedings of the National Academy of Sciences of the United States of America
  98 (8): 4622-4627; Apr 2001  
[Abstract]
[Full Text]

Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B
Salmeen A,
Andersen JN,
Myers MP,
Tonks NK,
Barford D

Molecular Cell
  6 (6): 1401-1412; Dec 2000  
[Abstract]
[Full Text]

Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro
Lavoie C,
Chevet E,
Roy L,
Tonks NK,
Fazel A,
Posner BI,
Paiement J,
Bergeron JJ

Proceedings of the National Academy of Sciences of the United States of America
  97 (25): 13637-13642; Dec 2000  
[Abstract]
[Full Text]

From structure to function of protein tyrosine phosphatases
Tonks NK

Abstracts of Papers of the American Chemical Society
  219 (0): U7-U7; Mar 2000  
[Full Text]

Structural assets of a tumor suppressor
Tonks NK,
Myers MP

Science
  286 (5447): 2096-7; Dec 10 1999  
[Full Text]

Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1
Zhang SH,
Liu J,
Kobayashi R,
Tonks NK

J Biol Chem
  274 (25): 17806-12; Jun 18 1999  
[Abstract]
[Full Text]

Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST
Garton AJ,
Tonks NK

J Biol Chem
  274 (6): 3811-8; Feb 5 1999  
[Abstract]
[Full Text]

Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of rat-1 fibroblasts and promotes differentiation of K562 cells
LaMontagne KR,
Hannon G,
Tonks NK

Proc Natl Acad Sci U S A
  95 (24): 14094-9; Nov 24 1998  
[Abstract]
[Full Text]

The lipid phosphatase activity of PTEN is critical for its tumor supressor function
Myers MP,
Pass I,
Batty IH,
Van der Kaay J,
Stolarov JP,
Hemmings BA,
Wigler MH,
Downes CP,
Tonks NK

Proc Natl Acad Sci U S A
  95 (23): 13513-8; Nov 10 1998  
[Abstract]
[Full Text]

Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo
LaMontagne KR,
Flint AJ,
Franza BR,
Pandergast AM,
Tonks NK

Mol Cell Biol
  18 (5): 2965-75; May 1998  
[Abstract]
[Full Text]

Dynamic interaction of PTPmu with multiple cadherins in vivo
Brady-Kalnay SM,
Mourton T,
Nixon JP,
Pietz GE,
Kinch M,
Chen H,
Brackenbury R,
Rimm DL,
Del Vecchio RL,
Tonks NK

J Cell Biol
  141 (1): 287-96; Apr 6 1998   PMCID: PMC2132733
[Abstract]
[Full Text] [PDF]

Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase
Tiganis T,
Bennett AM,
Ravichandran KS,
Tonks NK

Mol Cell Biol
  18 (3): 1622-34; Mar 1998  
[Abstract]
[Full Text]

The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development
Gutch MJ,
Flint AJ,
Keller J,
Tonks NK,
Hengartner MO

Genes Dev
  12 (4): 571-85; Feb 15 1998  
[Abstract]
[Full Text]

Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases
Bennett AM,
Tonks NK

Science
  278 (5341): 1288-91; Nov 14 1997  
[Abstract]
[Full Text]

Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein
Zhang SH,
Kobayashi R,
Graves PR,
Piwnica-Worms H,
Tonks NK

J Biol Chem
  272 (43): 27281-7; Oct 24 1997  
[Abstract]
[Full Text]

Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97
Tiganis T,
Flint AJ,
Adam SA,
Tonks NK

J Biol Chem
  272 (34): 21548-57; Aug 22 1997  
[Abstract]
[Full Text]

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
Myers MP,
Stolarov JP,
Eng C,
Li J,
Wang SI,
Wigler MH,
Parsons R,
Tonks NK

Proc Natl Acad Sci U S A
  94 (17): 9052-7; Aug 19 1997  
[Abstract]
[Full Text]

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition
Garton AJ,
Burnham MR,
Bouton AH,
Tonks NK

Oncogene
  15 (8): 877-85; Aug 18 1997  
[Abstract]
[Full Text]

Development of substrate-trapping mutants to identify physiological substrates of protein tyrosine phosphatases
Flint AJ,
Tiganis T,
Barford D,
Tonks NK

Proc Natl Acad Sci U S A
  94 (5): 1680-5; Mar 4 1997  
[Abstract]
[Full Text]

From form to function: signaling by protein tyrosine phosphatases
Tonks NK,
Neel BG

Cell
  87 (3): 365-8; Nov 1 1996  
[Full Text]

Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST
Garton AJ,
Flint AJ,
Tonks NK

Mol Cell Biol
  16 (11): 6408-18; Nov 1996  
[Abstract]
[Full Text]

Protein tyrosine phosphatases and the control of cellular signaling responses
Tonks NK

Adv Pharmacol
  36 (0): 91-119; 1996  
[Full Text]

Identification of the homophilic binding site of the receptor protein tyrosine phosphatase PTP mu
Brady-Kalnay SM,
Tonks NK

J Biol Chem
  269 (45): 28472-7; Nov 11 1994  
[Abstract]
[Full Text]

A Map Kinase-Dependent Spindle Assembly Checkpoint in Xenopus Egg Extracts
Minshull J,
Sun H,
Tonks NK,
Murray AW

Cell
  79 (3): 475-486; Nov 1994  
[Abstract]
[DOI] [Full Text]

The coordinated action of protein tyrosine phosphatases and kinases in cell signaling
Sun H,
Tonks NK

Trends Biochem Sci
  19 (11): 480-5; Nov 1994  
[Abstract]
[Full Text]

Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1
Sun H,
Tonks NK,
Bar-Sagi D

Science
  266 (5183): 285-8; Oct 14 1994  
[Abstract]
[Full Text]

Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density
Ostman A,
Yang Q,
Tonks NK

Proc Natl Acad Sci U S A
  91 (21): 9680-4; Oct 11 1994  
[Abstract]
[Full Text]

PTP-PEST: a protein tyrosine phosphatase regulated by serine phosphorylation
Garton AJ,
Tonks NK

Embo J
  13 (16): 3763-71; Aug 15 1994  
[Abstract]
[Full Text]

Characterization of two structurally related Xenopus laevis protein tyrosine phosphatases with homology to lipid-binding proteins
Del Vecchio RL,
Tonks NK

J Biol Chem
  269 (30): 19639-45; Jul 29 1994  
[Abstract]
[Full Text]

Purification and Crystallization of the Catalytic Domain of Human Protein-Tyrosine-Phosphatase 1b Expressed in Escherichia-Coli
Barford D,
Keller JC,
Flint AJ,
Tonks NK

Journal of Molecular Biology
  239 (5): 726-730; Jun 1994  
[Abstract]
[DOI] [Full Text]

Protein-Tyrosine Phosphatases and the Control of Cellular Signaling Responses
Tonks NK

Faseb Journal
  8 (7): A1377-A1377; Apr 1994  
[Full Text]

Crystal structure of human protein tyrosine phosphatase 1B
Barford D,
Flint AJ,
Tonks NK

Science
  263 (5152): 1397-1404; Mar 11 1994  
[Abstract]
[DOI] [Full Text]

Protein tyrosine phosphatases: from structure to function
Brady-Kalnay SM,
Tonks NK

Trends Cell Biol
  4 (3): 73-6; Mar 1994  
[Abstract]
[Full Text]

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
Sun H,
Charles CH,
Lau LF,
Tonks NK

Cell
  75 (3): 487-93; Nov 5 1993  
[Abstract]


Purification and characterization of the human protein tyrosine phosphatase, PTP mu, from a baculovirus expression system
Brady-Kalnay SM,
Tonks NK

Mol Cell Biochem
  127-1 (0): 131-41; Nov 1993  
[Abstract]


Differential Activities of Protein-Tyrosine Phosphatases in Intact-Cells
Lammers R,
Bossenmaier B,
Cool DE,
Tonks NK,
Schlessinger J,
Fischer EH,
Ullrich A

Journal of Biological Chemistry
  268 (30): 22456-22462; Oct 1993  
[Abstract]
[Full Text]

Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation
Brady-Kalnay SM,
Flint AJ,
Tonks NK

J Cell Biol
  122 (4): 961-72; Aug 1993  
[Abstract]


Interleukin-2 Regulates Raf-1 Kinase-Activity through a Tyrosine Phosphorylation-Dependent Mechanism in a T-Cell Line
Turner BC,
Tonks NK,
Rapp UR,
Reed JC

Proceedings of the National Academy of Sciences of the United States of America
  90 (12): 5544-5548; Jun 1993  
[Abstract]
[Full Text]

The Growth Factor-Inducible Immediate-Early Gene 3ch134 Encodes a Protein-Tyrosine-Phosphatase
Charles CH,
Sun H,
Lau LF,
Tonks NK

Proceedings of the National Academy of Sciences of the United States of America
  90 (11): 5292-5296; Jun 1993  
[Abstract]
[Full Text]

Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation
Flint AJ,
Gebbink MF,
Franza BR,
Hill DE,
Tonks NK

Embo J
  12 (5): 1937-46; May 1993  
[Abstract]


A Protein-Tyrosine Serine Phosphatase Encoded by the Genome of the Cyanobacterium Nostoc-Commune Utex-584
Potts M,
Sun H,
Mockaitis K,
Kennelly PJ,
Reed D,
Tonks NK

Journal of Biological Chemistry
  268 (11): 7632-7635; Apr 1993  
[Abstract]
[Full Text]

Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase
Yang Q,
Co D,
Sommercorn J,
Tonks NK

J Biol Chem
  268 (9): 6622-8; Mar 25 1993  
[Abstract]


Signal transduction and protein tyrosine dephosphorylation
Tonks NK,
Flint AJ,
Gebbink MF,
Sun H,
Yang Q

Adv Second Messenger Phosphoprotein Res
  28 (0): 203-10; 1993  


Cytokinetic Failure and Asynchronous Nuclear Division in Bhk Cells Overexpressing a Truncated Protein-Tyrosine-Phosphatase
Cool DE,
Andreassen PR,
Tonks NK,
Krebs EG,
Fischer EH,
Margolis RL

Proceedings of the National Academy of Sciences of the United States of America
  89 (12): 5422-5426; Jun 1992  
[Abstract]
[Full Text]

Sequential Dephosphorylation of a Multiply Phosphorylated Insulin-Receptor Peptide by Protein Tyrosine Phosphatases
Ramachandran C,
Aebersold R,
Tonks NK,
Pot DA

Biochemistry
  31 (17): 4232-4238; May 1992  
[Abstract]
[Full Text]

Protein tyrosine phosphatases: the problems of a growing family
Tonks NK,
Yang Q,
Flint AJ,
Gebbink MF,
Franza BR,
Hill DE,
Sun H,
Brady-Kalnay S

Cold Spring Harbor Symposia on Quantitative Biology LVII: The Cell Surface
  57 87-94; 1992  


Tyrosine Phosphatases and Their Possible Interplay with Tyrosine Kinases
Fischer EH,
Charbonneau H,
Cool DE,
Tonks NK

Ciba Foundation Symposia
  164 (0): 132-144; 1992  
[Abstract]
[Full Text]

1002 Protein Phosphatases
Charbonneau H,
Tonks NK

Annual Review of Cell Biology
  8 (0): 463-493; 1992  
[Full Text]

Protein-Tyrosine-Phosphatase-Cd45 Is Phosphorylated Transiently on Tyrosine Upon Activation of Jurkat T-Cells
Stover DR,
Charbonneau H,
Tonks NK,
Walsh KA

Proceedings of the National Academy of Sciences of the United States of America
  88 (17): 7704-7707; Sep 1991  
[Abstract]
[Full Text]

Plague, pox and tyrosine dephosphorylation
Tonks NK

Curr Biol
  1 (4): 259-61; Aug 1991  
[Full Text]

Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin
Yang Q,
Tonks NK

Proc Natl Acad Sci U S A
  88 (14): 5949-53; Jul 15 1991  
[Abstract]
[Full Text]

Purification and Characterization of a Human Recombinant T-Cell Protein-Tyrosine-Phosphatase from a Baculovirus Expression System
Zander NF,
Lorenzen JA,
Cool DE,
Tonks NK,
Daum G,
Krebs EG,
Fischer EH

Biochemistry
  30 (28): 6964-6970; Jul 1991  
[Abstract]
[Full Text]

Abnormal Regulation of Protein Tyrosine Phosphatase-Activities in Skeletal-Muscle of Insulin-Resistant Humans
McGuire MC,
Fields RM,
Nyomba BL,
Raz I,
Bogardus C,
Tonks NK,
Sommercorn J

Diabetes
  40 (7): 939-942; Jul 1991  
[Abstract]
[Full Text]

Protein Tyrosine Phosphatases - a Diverse Family of Intracellular and Transmembrane Enzymes
Fischer EH,
Charbonneau H,
Tonks NK

Science
  253 (5018): 401-406; Jul 1991  
[Abstract]
[Full Text]

Structure, regulation, and function of protein tyrosine phosphatases
Tonks NK,
Yang Q,
Guida P

Cold Spring Harb Symp Quant Biol
  56 (0): 265-73; 1991  
[Full Text]

Purification of Protein-Tyrosine Phosphatases from Human Placenta
Tonks NK,
Diltz CD,
Fischer EH

Methods in Enzymology
  201 (0): 427-442; 1991  
[Full Text]

Purification and Assay of Cd45 - an Integral Membrane Protein-Tyrosine Phosphatase
Tonks NK,
Diltz CD,
Fischer EH

Methods in Enzymology
  201 (0): 442-451; 1991  
[Full Text]

Protein phosphatases: key players in the regulation of cell function
Tonks NK

Curr Opin Cell Biol
  2 (6): 1114-24; Dec 1990  
[Full Text]


Page 1 of 1

Go back to Search Mode


Last Updated: November, 2017
Most Recent Publications: Jan 13, 2015

© 2012   CSHL Library and Archives   1 Bungtown Rd.   Cold Spring Harbor, NY 11724   Library Information 516-367-6872
CSHL Home Intranet