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13 Article(s) on File
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Double-stranded DNA in exosomes: a novel biomarker in cancer detection
Thakur BK,
Zhang H,
Becker A,
Matei I,
Huang Y,
Costa-Silva B,
Zheng Y,
Hoshino A,
Brazier H,
Xiang J,
Williams C,
Rodriguez-Barrueco R,
Silva JM,
Zhang W,
Hearn S,
Elemento O,
Paknejad N,
Manova-Todorova K,
Welte K,
Bromberg J,
Peinado H,
Lyden D

Cell Res
  24 (6): 766-9; Jun 2014   Nlm
[DOI] [Full Text]

Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells
Bardot ES,
Valdes VJ,
Zhang J,
Perdigoto CN,
Nicolis S,
Hearn SA,
Silva JM,
Ezhkova E

Embo Journal
  32 (14): 1990-2000; Jul 17 2013  
[DOI] [Full Text]

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
Freed-Pastor WA,
Mizuno H,
Zhao X,
Langerød A,
Moon SH,
Rodriguez-Barrueco R,
Barsotti A,
Chicas A,
Li W,
Polotskaia A,
Bissell MJ,
Osborne TF,
Tian B,
Lowe SW,
Silva JM,
Børresen-Dale AL,
Levine AJ,
Bargonetti J,
Prives C

Cell
  148 (1): 244-258; Jan 2012  
[Abstract]
[DOI] [Full Text]

Deep sequencing of target linkage assay-identified regions in familial breast cancer: Methods, analysis pipeline and troubleshooting
Rosa-Rosa JM,
Gracia-Azn√°rez FJ,
Hodges E,
Pita G,
Rooks M,
Xuan Z,
Bhattacharjee A,
Brizuela L,
Silva JM,
Hannon GJ,
Benitez J

PLoS ONE
  5 (4): e9976, 1-10; April 2010  
[Abstract]
[DOI]

Cyfip1 is a putative invasion suppressor in epithelial cancers
Silva JM,
Ezhkova E,
Silva J,
Heart S,
Castillo M,
Campos Y,
Castro V,
Bonilla F,
Cordon-Cardo C,
Muthuswamy SK,
Powers S,
Fuchs E,
Hannon GJ

Cell
  137 (6): 1047-61; Jun 12 2009   PMCID: PMC2754270
[Abstract]
[DOI] [Full Text] [PDF]

Profiling essential genes in human mammary cells by multiplex RNAi screening
Silva JM,
Marran K,
Parker JS,
Silva J,
Golding M,
Schlabach MR,
Elledge SJ,
Hannon GJ,
Chang K

Science
  319 (5863): 617-20; Feb 1 2008   PMC2981870
[Abstract]
[DOI] [Full Text] [PDF]

Second-generation shRNA libraries covering the mouse and human genomes
Silva JM,
Li MZ,
Chang K,
Ge W,
Golding MC,
Rickles RJ,
Siolas D,
Hu G,
Paddison PJ,
Schlabach MR,
Sheth N,
Bradshaw J,
Burchard J,
Kulkarni A,
Cavet G,
Sachidanandam R,
McCombie WR,
Cleary MA,
Elledge SJ,
Hannon GJ

Nat Genet
  37 (11): 1281-8; Nov 2005  
[Abstract]
[DOI] [Full Text]

Cloning of short hairpin RNAs for gene knockdown in mammalian cells
Paddison PJ,
Cleary M,
Silva JM,
Chang K,
Sheth N,
Sachidanandam R,
Hannon GJ

Nat Methods
  1 (2): 163-7; Nov 2004  
[DOI] [Full Text]

RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells
Silva JM,
Mizuno H,
Brady A,
Lucito R,
Hannon GJ

Proc Natl Acad Sci U S A
  101 (17): 6548-52; Apr 27 2004   PMCID: PMC404082
[Abstract]
[DOI] [Full Text] [PDF]

A resource for large-scale RNA-interference-based screens in mammals
Paddison PJ,
Silva JM,
Conklin DS,
Schlabach M,
Li M,
Aruleba S,
Balija V,
OShaughnessy A,
Gnoj L,
Scobie K,
Chang K,
Westbrook T,
Cleary M,
Sachidanandam R,
McCombie WR,
Elledge SJ,
Hannon GJ

Nature
  428 (6981): 427-31; Mar 25 2004  
[Abstract]
[DOI] [Full Text]

Free energy lights the path toward more effective RNAi
Silva JM,
Sachidanandam R,
Hannon GJ

Nature Genetics
  35 (4): 303-305; Dec 2003  
[Abstract]
[Full Text]

A micrococcal nuclease homologue in RNAi effector complexes
Caudy AA,
Ketting RF,
Hammond SM,
Denli AM,
Bathoorn AM,
Tops BB,
Silva JM,
Myers MM,
Hannon GJ,
Plasterk RH

Nature
  425 (6956): 411-414; Sep 2003  
[Abstract]
[DOI] [Full Text]

RNA interference: a promising approach to antiviral therapy?
Silva JM,
Hammond SM,
Hannon GJ

Trends in Molecular Medicine
  8 (11): 505-508; Nov 2002  
[Full Text]


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