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9 Article(s) on File
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In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
Rudalska R,
Dauch D,
Longerich T,
McJunkin K,
Wuestefeld T,
Kang TW,
Hohmeyer A,
Pesic M,
Leibold J,
von Thun A,
Schirmacher P,
Zuber J,
Weiss KH,
Powers S,
Malek NP,
Eilers M,
Sipos B,
Lowe SW,
Geffers R,
Laufer S,
Zender L

Nature Medicine
  20 (10): 1138-1146; Oct 2014   NLM
[Abstract]
[DOI] [Full Text]

A pipeline for the generation of shRNA transgenic mice
Dow LE,
Premsrirut PK,
Zuber J,
Fellmann C,
McJunkin K,
Miething C,
Park Y,
Dickins RA,
Hannon GJ,
Lowe SW

Nat Protoc
  7 (2): 374-93; Feb 2 2012   NLM
[Abstract]
[DOI] [Full Text]

Reversible suppression of an essential gene in adult mice using transgenic RNA interference
McJunkin K,
Mazurek A,
Premsrirut PK,
Zuber J,
Dow LE,
Simon J,
Stillman B,
Lowe SW

Proc Natl Acad Sci U S A
  108 (17): 7113-7118; Apr 26 2011   NLM PMC3084121
[Abstract]
[DOI]

Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
Fellmann C,
Zuber J,
McJunkin K,
Chang K,
Malone CD,
Dickins R,
Xu Q,
Hengartner M,
Elledge SJ,
Hannon GJ,
Lowe SW

Molecular Cell
  41 (6): 733-746; Mar 18 2011   Array
[Abstract]
[DOI]

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
Zuber J,
McJunkin K,
Fellmann C,
Dow L,
Taylor MJ,
Hannon GJ,
Lowe SW

Nature Biotechnology
  29 (1): 79-85; Jan 2011  
[Abstract]
[DOI] [Full Text] [PDF]

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
Mavrakis KJ,
Wolfe AL,
Oricchio E,
Palomero T,
de Keersmaecker K,
McJunkin K,
Zuber J,
James T,
Chang K,
Khan AA,
Leslie CS,
Parker JS,
Paddison PJ,
Tam W,
Ferrando A,
Wendel HG

Nature Cell Biology
  12 (4): 372-U159; Apr 2010   PMCID: PMC2989719
[Abstract]
[DOI] [Full Text] [PDF]

miR-221 overexpression contributes to liver tumorigenesis
Pineau P,
Volinia S,
McJunkin K,
Marchio A,
Battiston C,
Terris B,
Mazzaferro V,
Lowe SW,
Croce CM,
Dejean A

Proceedings of the National Academy of Sciences of the United States of America
  107 (1): 264-269; Jan 5 2010   PMCID: PMC2806773
[Abstract]
[DOI] [Full Text] [PDF]

Tissue-specific and reversible RNA interference in transgenic mice
Dickins RA,
McJunkin K,
Hernando E,
Premsrirut PK,
Krizhanovsky V,
Burgess DJ,
Kim SY,
Cordon-Cardo C,
Zender L,
Hannon GJ,
Lowe SW

Nat Genet
  39 (7): 914 - 921; Jul 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Tetracycline-regulated p53 knockdown in cells and transgenic mice
Dickins RA,
Premsrirut PK,
McJunkin K,
Kim SY,
Hannon GJ,
Lowe SW

Toxicologic Pathology
  34 (7): 1006-1006; 2006  
[Full Text]


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