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40 Article(s) on File
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Missing-in-Metastasis regulates cell motility and invasion via PTPdelta-mediated changes in SRC activity
Chaudhary F,
Lucito R,
Tonks NK

Biochemical Journal
  (0): Oct 7 2014   Nlm
[Abstract]
[DOI] [Full Text]

Integrative prediction of gene function and platinum-free survival from genomic and epigenetic features in ovarian cancer
Wrzeszczynski KO,
Varadan V,
Kamalakaran S,
Levine DA,
Dimitrova N,
Lucito R

Methods Mol Biol
  1049 (0): 35-51; Aug 2013   NLM
[Abstract]
[DOI] [Full Text]

Protein Tyrosine Phosphatase 1B Antagonized Signaling by IGF-1 Receptor and BRK/PTK6 in Ovarian Cancer Cells
Fan G,
Lin G,
Lucito R,
Tonks NK

J Biol Chem
  288 (34): 24923-24934; Aug 2013   NLM
[Abstract]
[DOI] [Full Text]

Two Distinct Categories of Focal Deletions in Cancer Genomes
Rajaram M,
Zhang J,
Wang T,
Li J,
Kuscu C,
Qi H,
Kato M,
Grubor V,
Weil RJ,
Helland A,
Borrenson-Dale AL,
Cho KR,
Levine DA,
Houghton AN,
Wolchok JD,
Myeroff L,
Markowitz SD,
Lowe SW,
Zhang M,
Krasnitz A,
Lucito R,
Mu D,
Powers RS

PLoS ONE
  8 (6): e66264; Jun 21 2013   NLM
[Abstract]
[DOI] [Full Text]

Proteomic identification of carboplatin resistance in ovarian cancer cells
Wrzeszczynski KO,
Fan GF,
Fu CX,
Pappin DJ,
Lucito R,
Tonks NK

Cancer Research
  73 (8): 2502; Apr 2013  
[Abstract]
[DOI] [Full Text]

Identification of Tumor Suppressors and Oncogenes from Genomic and Epigenetic Features in Ovarian Cancer
Wrzeszczynski KO,
Varadan V,
Byrnes J,
Lum E,
Kamalakaran S,
Levine DA,
Dimitrova N,
Zhang MQ,
Lucito R

PLoS ONE
  6 (12): Dec 2011  
[Abstract]
[DOI] [Full Text]

DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables
Kamalakaran S,
Varadan V,
Giercksky Russnes HE,
Levy D,
Kendall JT,
Janevski A,
Riggs M,
Banerjee N,
Synnestvedt M,
Schlichting E,
KÃ¥resen R,
Shama Prasada K,
Rotti H,
Rao R,
Rao L,
Eric Tang MH,
Satyamoorthy K,
Lucito R,
Wigler MH,
Dimitrova N,
Naume B,
Borresen-Dale AL,
Hicks JB

Molecular Oncology
  5 (1): 77-92; Feb 2011  
[Abstract]
[DOI] [Full Text] [PDF]

Testing and Validating High Throughput Genomic Analysis of FFPE Samples: Systematic Gene Expression Differences between Matched Frozen and FFPE Samples Due to Rapid mRNA Degradation Signals
Cabal R,
Khanin R,
Viali A,
Socci N,
Lucito R,
Olshen A,
Zhang J,
Gerald W,
Powers S,
Ladanyi M

Modern Pathology
  24 (0): 1875; Feb 2011  
[Full Text]

Pathway and network analysis probing epigenetic influences on chemosensitivity in ovarian cancer
Banerjee N,
Janevski A,
Kamalakaran S,
Varadan V,
Lucito R,
Dimitrova N

  2010   Elsevier
[Abstract]
[DOI] [Full Text]

Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
Kamalakaran S,
Kendall JT,
Zhao X,
Tang C,
Khan S,
Ravi K,
Auletta T,
Riggs M,
Wang Y,
Helland A,
Naume B,
Dimitrova N,
Borresen-Dale AL,
Hicks JB,
Lucito R

Nucl. Acids Res.
  37 (12): e89; Jul 2009   PMCID: PMC2709589
[Abstract]
[DOI] [Full Text] [PDF]

Comparative genomic hybridization by representational oligonucleotide microarray analysis
Lucito R,
Byrnes J

Methods Mol Biol
  556 (0): 33-46; Feb 1 2009  
[Abstract]
[DOI] [Full Text]

Genomic events associated with progression of pleural malignant mesothelioma
Ivanov SV,
Miller J,
Lucito R,
Tang CL,
Ivanova AV,
Pei JM,
Carbone M,
Cruz C,
Beck A,
Webb C,
Nonaka D,
Testa JR,
Pass HI

International Journal of Cancer
  124 (3): 589-599; Feb 2009   PMCID: PMC2920182
[Abstract]
[DOI] [Full Text] [PDF]

Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification
Chen S,
Auletta T,
Dovirak O,
Hutter C,
Kuntz K,
El-Ftesi S,
Kendall JT,
Han H,
Von Hoff DD,
Ashfaq R,
Maitra A,
Iacobuzio-Donahue CA,
Hruban RH,
Lucito R

Cancer Biol Ther
  7 (11): 1793-1798; Nov 21 2008  
[Abstract]
[Full Text]

Frequent genomic copy number gain and overexpression of GATA-6 in pancreatic carcinoma
Fu B,
Luo M,
Lakkur S,
Lucito R,
Iacobuzio-Donahue CA

Cancer Biol Ther
  7 (10): 1593-601; Oct 2008  
[Abstract]
[Full Text]

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma
Xue W,
Krasnitz A,
Lucito R,
Sordella R,
Van Aelst L,
Cordon-Cardo C,
Singer S,
Kuehnel F,
Wigler MH,
Powers S,
Zender L,
Lowe SW

Genes Dev
  22 (11): 1439-44; Jun 1 2008   PMCID: PMC2418580
[Abstract]
[DOI] [Full Text] [PDF]

High-content analysis of cancer genome DNA alterations
Degenhardt YY,
Wooster R,
McCombie RW,
Lucito R,
Powers S

Current Opinion in Genetics Development
  18 (1): 68-72; Feb 2008   PMCID: PMC2729060
[Abstract]
[DOI] [Full Text] [PDF]

Copy-Number Variants in Patients with a Strong Family History of Pancreatic Cancer
Lucito R,
Suresh S,
Walter K,
Pandey A,
Lakshmi B,
Krasnitz A,
Sebat J,
Wigler MH,
Klein AP,
Brune K,
Palmisano E,
Maitra A,
Goggins M,
Hruban RH

Cancer Biol Ther
  6 (10): 1592-9; Oct 2007  
[Abstract]
[DOI] [Full Text]

High-resolution ROMA analysis of chromosomal rearrangements in mesothelioma patients with poor and good survival
Ivanov SV,
Ivanova AV,
Lucito R,
Pass HI

Journal of Thoracic Oncology
  2 (8): S431-S431; Aug 2007  
[Full Text]

Identification of alterations in DNA copy number in host stromal cells during tumor progression
Pelham RJ,
Rodgers L,
Hall IM,
Lucito R,
Nguyen KC,
Navin NE,
Hicks JB,
Mu D,
Powers S,
Wigler MH,
Botstein D

Proc Natl Acad Sci U S A
  103 (52): 19848-19853; Dec 2006  
[Abstract]
[DOI] [Full Text]

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
Zender L,
Spector MS,
Xue W,
Flemming P,
Cordon-Cardo C,
Silke J,
Fan ST,
Luk JM,
Wigler MH,
Hannon GJ,
Mu D,
Lucito R,
Powers S,
Lowe SW

Cell
  125 (7): 1253-67; Jun 30 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers
Geurts AM,
Collier LS,
Geurts JL,
Oseth LL,
Bell ML,
Mu D,
Lucito R,
Godbout SA,
Green LE,
Lowe SW,
Hirsch BA,
Leinwand LA,
Largaespada DA

PLoS Genetics
  2 (9): 1413-1423; 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Representational oligonucleotide microarray (ROMA) identifies cIAP1/cIAP2 as candidate oncogenes in mouse and human hepatocarcinogenesis-validation of cIAP1 as a therapeutic target in liver cancer in a new mouse model of hepatocellular carcinoma
Zender L,
Spector MS,
Xue W,
Flemming P,
Mu D,
Cordon-Cardo C,
Powers S,
Hannon GJ,
Lucito R,
Lowe SW

Hepatology
  42 (4): 244A-244A; Oct 2005  
[Full Text]

Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms tumor
Prawitt D,
Enklaar T,
Gartner-Rupprecht B,
Spangenberg C,
Oswald M,
Lausch E,
Schmidtke P,
Reutzel D,
Fees S,
Lucito R,
Korzon M,
Brozek L,
Limon J,
Housman DE,
Pelletier J,
Zabel B

Proc Natl Acad Sci U S A
  102 (11): 4085-4090; Mar 2005  
[Abstract]
[DOI] [Full Text]

Generation and Analysis of Genetically Defined Liver Carcinomas Derived from Bipotential Liver Progenitors
Zender L,
Xue W,
Cordon-Cardo C,
Hannon GJ,
Lucito R,
Powers S,
Flemming P,
Spector MS,
Lowe SW

Cold Spring Harbor Symposia on Quantitative Biology VXX: Molecular approaches to controlling cancer
  70 251-261; 2005  
[Abstract]
[DOI] [Full Text] [PDF]

A versatile statistical analysis algorithm to detect genome copy number variation
Daruwala RS,
Rudra A,
Ostrer H,
Lucito R,
Wigler MH,
Mishra B

Proceedings of the National Academy of Sciences of the United States of America
  101 (46): 16292-16297; Nov 2004  
[Abstract]
[DOI] [Full Text]

Circular binary segmentation for the analysis of array-based DNA copy number data
Olshen AB,
Venkatraman ES,
Lucito R,
Wigler MH

Biostatistics
  5 (4): 557-572; Oct 2004  
[Abstract]
[DOI] [Full Text]

Large-scale copy number polymorphism in the human genome
Sebat J,
Lakshmi B,
Troge JE,
Alexander J,
Young J,
Lundin P,
Maner S,
Massa H,
Walker M,
Chi M,
Navin NE,
Lucito R,
Healy J,
Hicks JB,
Ye K,
Reiner A,
Gilliam TC,
Trask B,
Patterson N,
Zetterberg A,
Wigler MH

Science
  305 (5683): 525-8; Jul 23 2004  
[Abstract]
[DOI] [Full Text]

RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells
Silva JM,
Mizuno H,
Brady A,
Lucito R,
Hannon GJ

Proc Natl Acad Sci U S A
  101 (17): 6548-52; Apr 27 2004   PMCID: PMC404082
[Abstract]
[DOI] [Full Text] [PDF]

Representational oligonucleotide microarray analysis: A high-resolution method to detect genome copy number variation
Lucito R,
Healy J,
Alexander J,
Reiner A,
Esposito D,
Chi MY,
Rodgers L,
Brady A,
Sebat J,
Troge JE,
West JA,
Rostan S,
Nguyen KC,
Powers S,
Ye KQ,
Olshen A,
Venkatraman E,
Norton L,
Wigler MH

Genome Research
  13 (10): 2291-2305; Oct 2003  
[Abstract]
[DOI] [Full Text]

Preparation of slides and hybridization
Lucito R,
Wigler MH
In:
DNA microarrays : a molecular cloning manual
(eds. Bowtell, D. Sambrook, J.) Cold Spring Harbor, NY: Cold Spring Harbor L; 2003. : 394-399  


Preparation of target DNA
Lucito R,
Wigler MH
In:
DNA microarrays : a molecular cloning manual
(eds. Bowtell, D. Sambrook, J.) Cold Spring Harbor, NY: Cold Spring Harbor L; 2003. : 386-393  


Using cDNA-representational difference analysis (cDNA-RDA) in combination with microarrays to identify Rac regulated genes
Schmitz AA,
Lucito R,
Van Aelst L
In:
GTPase Protocols: the Ras superfamily
(eds. ) : Humana Press; 2002. 189: 25-43  
[DOI] [Full Text]

Detecting gene copy number fluctuations in tumor cells by microarray analysis of genomic representations
Lucito R,
West J,
Reiner A,
Alexander J,
Esposito D,
Mishra B,
Powers S,
Norton L,
Wigler MH

Genome Research
  10 (11): 1726-1736; Nov 2000  
[Abstract]
[Full Text]

Genetic analysis using genomic representations
Lucito R,
Nakimura M,
West JA,
Han Y,
Chin K,
Jensen KR,
McCombie RW,
Gray JW,
Wigler MH

Proc Natl Acad Sci U S A
  95 (8): 4487-92; Apr 14 1998  
[Abstract]
[Full Text]

Transcriptional activation by the hepatitis B virus X protein
Lucito R,
Schneider RJ
In:
Regulation of gene expression in animal viruses
(eds. Carrasco,Luis Sonenberg,Nahum Wimmer,Eckard ) New York: Plenum Press; 1993. : 67-80  


Alternate translation initiation on hepatitis B virus X mRNA produces multiple polypeptides that differentially transactivate class II and III promoters
Kwee L,
Lucito R,
Aufiero B,
Schneider RJ

J Virol
  66 (7): 4382-9; Jul 1992  
[Abstract]
[Full Text]

Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C
Lucito R,
Schneider RJ

J Virol
  66 (2): 983-91; Feb 1992  
[Abstract]
[Full Text]

Elements required for transcription initiation of the human U2 snRNA gene coincide with elements required for snRNA 3 end formation
Hernandez N,
Lucito R

Embo J
  7 (10): 3125-34; Oct 1988  
[Abstract]
[Full Text]

Formation of the 3 End of Small Nuclear Rnas
Lobo SM,
Lucito R,
Hernandez N

Journal of Cellular Biochemistry - Supplement.(12 PART D)
  (0): 211; 1988  


Formation of the 3 End of Snrnas
Hernandez N,
Lucito R

Molecular Biology Reports
  12 (3): 145-145; 1987  
[Full Text]


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