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17 Article(s) on File
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SnapShot: Genetic mouse models of cancer
Zender L,
Zuber J,
Lowe SW

Cell
  129 (4): 838-838; May 2007  
[DOI] [Full Text] [PDF]

Genetic mechanisms of cytarabine resistance in leukemia: cell culture and mouse transplantation models
Yin B,
Diers MD,
Rathe SK,
Lowe SW,
Largaespada DA

ASH Annual Meeting Abstracts
  108 (11): 4374; Nov 16 2006  
[Abstract]
[Full Text]

A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation
Narita M,
Krizhanovsky V,
Nunez S,
Chicas A,
Hearn SA,
Myers MP

Cell
  126 (3): 503-14; Aug 11 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo
Wendel H,
Malina A,
Zhao Z,
Zender L,
Kogan SC,
Cordon-Cardo C,
Pelletier J,
Lowe SW

Cancer Res
  66 (15): 7639-46; Aug 1 2006  
[Abstract]
[DOI] [Full Text] [PDF]

The p53-Bcl-2 connection
Hemann MT,
Lowe SW

Cell Death Differ
  13 (8): 1256-9; Aug 2006  
[DOI] [Full Text] [PDF]

Mouse genomic representational oligonucleotide microarray analysis: detection of copy number variations in normal and tumor specimens
Lakshmi B,
Hall IM,
Egan C,
Alexander J,
Leotta A,
Healy J,
Zender L,
Spector MS,
Xue W,
Lowe SW,
Wigler M,
Lucito R

Proc Natl Acad Sci U S A
  103 (30): 11234-9; Jul 25 2006   PMCID: PMC1544071
[Abstract]
[DOI] [Full Text] [PDF]

Loss of p53 impedes the antileukemic response to BCR-ABL inhibition
Wendel H,
de Stanchina E,
Cepero E,
Ray S,
Emig M,
Fridman JS,
Veach DR,
Bornmann WG,
Clarkson B,
McCombie WR,
Kogan SC,
Hochhaus A,
Lowe SW

Proc Natl Acad Sci U S A
  103 (19): 7444-9; May 9 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Defined genetic events associated with the spontaneous in vitro transformation of ElA/Ras-expressing human IMR90 fibroblasts
Mason DX,
Keppler D,
Zhang J,
Jackson TJ,
Seger YR,
Matsui S,
Abreo F,
Cowell JK,
Hannon GJ,
Lowe SW,
Lin AW

Carcinogenesis
  27 (2): 350-359; Feb 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations
Ramiro AR,
Jankovic M,
Callen E,
Difilippantonio S,
Chen H,
McBride KM,
Eisenreich TR,
Chen J,
Dickins RA,
Lowe SW,
Nussenzweig A,
Nussenzweig MC

Nature
  440 (7080): 105-109; 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils
Martinelli S,
Kostylina G,
Niggli V,
Baumann C,
Fey MF,
Wendel HG,
Lowe SW,
Yousefi S,
Simon HU

Oncogene
  25 (52): 6915-6923; 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
Dickins RA,
Hemann MT,
Zilfou JT,
Simpson DR,
Ibarra I,
Hannon GJ,
Lowe SW

Nat Genet
  37 (11): 1289-95; Nov 2005  
[Abstract]
[DOI] [Full Text] [PDF]

p63 deficiency activates a program of cellular senescence and leads to accelerated aging
Keyes WM,
Wu Y,
Vogel H,
Guo X,
Lowe SW,
Mills AA

Genes Dev
  19 (17): 1986-99; Sep 1 2005  
[Abstract]
[DOI]

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
Hemann MT,
Bric A,
Teruya-Feldstein J,
Herbst A,
Nilsson JA,
Cordon-Cardo C,
Cleveland JL,
Tansey WP,
Lowe SW

Nature
  436 (7052): 807-11; Aug 11 2005  
[Abstract]
[DOI] [Full Text] [PDF]

A microRNA polycistron as a potential human oncogene
He L,
Thomson JM,
Hemann MT,
Hernando-Monge E,
Mu D,
Goodson S,
Powers S,
Cordon-Cardo C,
Lowe SW,
Hannon GJ,
Hammond SM

Nature
  435 (7043): 828-33; Jun 9 2005  
[Abstract]
[DOI] [Full Text] [PDF]

A conserved element in Myc that negatively regulates its proapoptotic activity
Herbst A,
Hemann MT,
Tworkowski KA,
Salghetti SE,
Lowe SW,
Tansey WP

EMBO Rep
  6 (2): 177-83; Feb 2005  
[Abstract]
[DOI] [Full Text] [PDF]

Direct coupling of the cell cycle and cell death machinery by E2F
Nahle Z,
Polakoff J,
Davuluri RV,
McCurrach ME,
Jacobson MD,
Narita M,
Zhang MQ,
Lazebnik Y,
Bar-Sagi D,
Lowe SW

Nat Cell Biol
  4 (11): 859-864; 2002  
[Abstract]
[DOI] [Full Text]

E1A signaling to p53 involves the p19(ARF) tumor suppressor
de Stanchina E,
McCurrach ME,
Zindy F,
Shieh S,
Ferbeyre G,
Samuelson AV,
Prives C,
Roussel MF,
Sherr CJ,
Lowe SW

Genes Dev
  12 (15): 2434-42; Aug 1 1998  
[Abstract]
[DOI] [Full Text] [PDF]


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