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22 Article(s) on File
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Development of siRNA payloads to target KRAS-mutant cancer
Yuan TL,
Fellmann C,
Lee CS,
Ritchie CD,
Thapar V,
Lee LC,
Hsu DJ,
Grace D,
Carver JO,
Zuber J,
Luo J,
McCormick F,
Lowe SW

Cancer Discovery
  4 (10): 1182; Oct 1 2014   Nlm
[Abstract]
[DOI] [Full Text]

Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel
Delaneau O,
Marchini J,
McVeanh GA,
Donnelly P,
Lunter G,
Marchini JL,
Myers S,
Gupta-Hinch A,
Iqbal Z,
Mathieson I,
Rimmer A,
Xifara DK,
Kerasidou A,
Churchhouse C,
Altshuler DM,
Gabriel SB,
Lander ES,
Gupta N,
Daly MJ,
DePristo MA,
Banks E,
Bhatia G,
Carneiro MO,
Del Angel G,
Genovese G,
Handsaker RE,
Hartl C,
McCarroll SA,
Nemesh JC,
Poplin RE,
Schaffner SF,
Shakir K,
Sabeti PC,
Grossman SR,
Tabrizi S,
Tariyal R,
Li H,
Reich D,
Durbin RM,
Hurles ME,
Balasubramaniam S,
Burton J,
Danecek P,
Keane TM,
Kolb-Kokocinski A,
McCarthy S,
Stalker J,
Quail M,
Ayub Q,
Chen Y,
Coffey AJ,
Colonna V,
Huang N,
Jostins L,
Scally A,
Walter K,
Xue Y,
Zhang Y,
Blackburne B,
Lindsay SJ,
Ning Z,
Frankish A,
Harrow J,
Chris TS,
Abecasis GR,
Kang HM,
Anderson P,
Blackwell T,
Busonero F,
Fuchsberger C,
Jun G,
Maschio A,
Porcu E,
Sidore C,
Tan A,
Trost MK,
Bentley DR,
Grocock R,
Humphray S,
James T,
Kingsbury Z,
Bauer M,
Cheetham RK,
Cox T,
Eberle M,
Murray L,
Shaw R,
Chakravarti A,
Clark AG,
Keinan A,
Rodriguez-Flores JL,
De LaVega FM,
Degenhardt J,
Eichler EE,
Flicek P,
Clarke L,
Leinonen R,
Smith RE,
Zheng-Bradley X,
Beal K,
Cunningham F,
Herrero J,
McLaren WM,
Ritchie GR,
Barker J,
Kelman G,
Kulesha E,
Radhakrishnan R,
Roa A,
Smirnov D,
Streeter I,
Toneva I,
Gibbs RA,
Dinh H,
Kovar C,
Lee S,
Lewis L,
Muzny D,
Reid J,
Wang M,
Yu F,
Bainbridge M,
Challis D,
Evani US,
Lu J,
Nagaswamy U,
Sabo A,
Wang Y,
Yu J,
Fowler G,
Hale W,
Kalra D,
Green ED,
Knoppers BM,
Korbel JO,
Rausch T,
Sttz AM,
Lee C,
Griffin L,
Hsieh CH,
Mills RE,
Von Grotthuss M,
Zhang C,
Shi X,
Lehrach H,
Sudbrak R,
Amstislavskiy VS,
Lienhard M,
Mertes F,
Sultan M,
Timmermann B,
Yaspo ML,
Herwig SR,
Mardis ER,
Wilson RK,
Fulton L,
Fulton R,
Weinstock GM,
Chinwalla A,
Ding L,
Dooling D,
Koboldt DC,
McLellan MD,
Wallis JW,
Wendl MC,
Zhang Q,
Marth GT,
Garrison EP,
Kural D,
Lee WP,
Leong WF,
Ward AN,
Wu J,
Zhang M,
Nickerson DA,
Alkan C,
Hormozdiari F,
Ko A,
Sudmant PH,
Schmidt JP,
Davies CJ,
Gollub J,
Webster T,
Wong B,
Zhan Y,
Sherry ST,
Xiao C,
Church D,
Ananiev V,
Belaia Z,
Beloslyudtsev D,
Bouk N,
Chen C,
Cohen R,
Cook C,
Garner J,
Hefferon T,
Kimelman M,
Liu C,
Lopez J,
Meric P,
Ostapchuk Y,
Phan L,
Ponomarov S,
Schneider V,
Shekhtman E,
Sirotkin K,
Slotta D,
Zhang H,
Wang J,
Fang X,
Guo X,
Jian M,
Jiang H,
Jin X,
Li G,
Li J,
Li Y,
Liu X,
Lu Y,
Ma X,
Tai S,
Tang M,
Wang B,
Wang G,
Wu H,
Wu R,
Yin Y,
Zhang W,
Zhao J,
Zhao M,
Zheng X,
Lachlan H,
Fang L,
Li Q,
Li Z,
Lin H,
Liu B,
Luo R,
Shao H,
Xie Y,
Ye C,
Yu C,
Zheng H,
Zhu H,
Cai H,
Cao H,
Su Y,
Tian Z,
Yang H,
Yang L,
Zhu J,
Cai Z,
Albrecht MW,
Borodina TA,
Auton A,
Yoon SC,
Lihm J,
Makarov V,
Jin H,
Kim W,
Kim KC,
Gottipati S,
Jones D,
Cooper DN,
Ball EV,
Stenson PD,
Barnes B,
Kahn S,
Ye K,
Batzer MA,
Konkel MK,
Walker JA,
MacArthur DG,
Lek M,
Shriver MD,
Bustamante CD,
Gravel S,
Kenny EE,
Kidd JM,
Lacroute P,
Maples BK,
Moreno-Estrada A,
Zakharia F,
Henn B,
Sandoval K,
Byrnes JK,
Halperin E,
Baran Y,
Craig DW,
Christoforides A,
Izatt T,
Kurdoglu AA,
Sinari SA,
Homer N,
Squire K,
Sebat J,
Bafna V,
Burchard EG,
Hernandez RD,
Gignoux CR,
Haussler D,
Katzman SJ,
Kent WJ,
Howie B,
Ruiz-Linares A,
Dermitzakis ET,
Lappalainen T,
Devine SE,
Maroo A,
Tallon LJ,
Rosenfeld JA,
Michelson LP,
Angius A,
Cucca F,
Sanna S,
Bigham A,
Jones C,
Reinier F,
Lyons R,
Schlessinger D,
Awadalla P,
Hodgkinson A,
Oleksyk TK,
Martinez-Cruzado JC,
Fu Y,
Xiong M,
Jorde L,
Witherspoon D,
Xing J,
Browning BL,
Hajirasouliha I,
Chen K,
Albers CA,
Gerstein MB,
Abyzov A,
Chen J,
Habegger L,
Harmanci AO,
Mu XJ,
Sisu C,
Balasubramanian S,
Jin M,
Khurana E,
Clarke D,
Michaelson JJ,
Osullivan C,
Barnes KC,
Gharani N,
Toji LH,
Gerry N,
Kaye JS,
Kent A,
Mathias R,
Ossorio PN,
Parker M,
Rotimi CN,
Royal CD,
Tishkoff S,
Via M,
Bodmer W,
Bedoya G,
Yang G,
You CJ,
Garcia-Montero A,
Orfao A,
Dutil J,
Brooks LD,
Felsenfeld AL

Nature Communications
  5 (0): Jun 13 2014   Elsevier
[Abstract]
[DOI] [Full Text]

An integrated map of genetic variation from 1,092 human genomes
Altshuler DM,
Durbin RM,
Abecasis GR,
Bentley DR,
Chakravarti A,
Clark AG,
Donnelly P,
Eichler EE,
Flicek P,
Gabriel SB,
Gibbs RA,
Green ED,
Hurles ME,
Knoppers BM,
Korbel JO,
Lander ES,
Lee C,
Lehrach H,
Mardis ER,
Marth GT,
McVean GA,
Nickerson DA,
Schmidt JP,
Sherry ST,
Wang J,
Wilson RK,
Dinh H,
Kovar C,
Lee S,
Lewis L,
Muzny D,
Reid J,
Wang M,
Fang XD,
Guo XS,
Jian M,
Jiang H,
Jin X,
Li GQ,
Li JX,
Li YR,
Li Z,
Liu X,
Lu Y,
Ma XD,
Su Z,
Tai SS,
Tang MF,
Wang B,
Wang GB,
Wu HL,
Wu RH,
Yin Y,
Zhang WW,
Zhao J,
Zhao MR,
Zheng XL,
Zhou Y,
Gupta N,
Clarke L,
Leinonen R,
Smith RE,
Zheng-Bradley X,
Grocock R,
Humphray S,
James T,
Kingsbury Z,
Sudbrak R,
Albrecht MW,
Amstislavskiy VS,
Borodina TA,
Lienhard M,
Mertes F,
Sultan M,
Timmermann B,
Yaspo ML,
Fulton L,
Fulton R,
Weinstock GM,
Balasubramaniam S,
Burton J,
Danecek P,
Keane TM,
Kolb-Kokocinski A,
McCarthy S,
Stalker J,
Quail M,
Davies CJ,
Gollub J,
Webster T,
Wong B,
Zhan YP,
Auton A,
Yu F,
Bainbridge M,
Challis D,
Evani US,
Lu J,
Nagaswamy U,
Sabo A,
Wang Y,
Yu J,
Coin LJ,
Fang L,
Li QB,
Li ZY,
Lin HX,
Liu BH,
Luo RB,
Qin N,
Shao HJ,
Wang BQ,
Xie YL,
Ye C,
Yu C,
Zhang F,
Zheng HC,
Zhu HM,
Garrison EP,
Kural D,
Lee WP,
Leong WF,
Ward AN,
Wu JT,
Zhang MY,
Griffin L,
Hsieh CH,
Mills RE,
Shi XH,
von Grotthuss M,
Zhang CS,
Daly MJ,
DePristo MA,
Banks E,
Bhatia G,
Carneiro MO,
del Angel G,
Genovese G,
Handsaker RE,
Hartl C,
McCarroll SA,
Nemesh JC,
Poplin RE,
Schaffner SF,
Shakir K,
Yoon SC,
Lihm J,
Makarov V,
Jin HJ,
Kim W,
Kim KC,
Rausch T,
Beal K,
Cunningham F,
Herrero J,
McLaren WM,
Ritchie GR,
Gottipati S,
Keinan A,
Rodriguez-Flores JL,
Sabeti PC,
Grossman SR,
Tabrizi S,
Tariyal R,
Cooper DN,
Ball EV,
Stenson PD,
Barnes B,
Bauer M,
Cheetham RK,
Cox T,
Eberle M,
Kahn S,
Murray L,
Peden J,
Shaw R,
Ye K,
Batzer MA,
Konkel MK,
Walker JA,
MacArthur DG,
Lek M,
Herwig R,
Shriver MD,
Bustamante CD,
Byrnes JK,
De la Vega FM,
Gravel S,
Kenny EE,
Kidd JM,
Lacroute P,
Maples BK,
Moreno-Estrada A,
Zakharia F,
Halperin E,
Baran Y,
Craig DW,
Christoforides A,
Homer N,
Izatt T,
Kurdoglu AA,
Sinari SA,
Squire K,
Xiao CL,
Sebat J,
Bafna V,
Burchard EG,
Hernandez RD,
Gignoux CR,
Haussler D,
Katzman SJ,
Kent WJ,
Howie B,
Ruiz-Linares A,
Dermitzakis ET,
Lappalainen T,
Devine SE,
Liu XY,
Maroo A,
Tallon LJ,
Rosenfeld JA,
Michelson LP,
Kang HM,
Anderson P,
Angius A,
Bigham A,
Blackwell T,
Busonero F,
Cucca F,
Fuchsberger C,
Jones C,
Jun G,
Li Y,
Lyons R,
Maschio A,
Porcu E,
Reinier F,
Sanna S,
Schlessinger D,
Sidore C,
Tan A,
Trost MK,
Awadalla P,
Hodgkinson A,
Lunter G,
Marchini JL,
Myers S,
Churchhouse C,
Delaneau O,
Gupta-Hinch A,
Iqbal Z,
Mathieson I,
Rimmer A,
Xifara DK,
Oleksyk TK,
Fu YX,
Liu XM,
Xiong MM,
Jorde L,
Witherspoon D,
Xing JC,
Browning BL,
Alkan C,
Hajirasouliha I,
Hormozdiari F,
Ko A,
Sudmant PH,
Chen K,
Chinwalla A,
Ding L,
Dooling D,
Koboldt DC,
McLellan MD,
Wallis JW,
Wendl MC,
Zhang QY,
Tyler-Smith C,
Albers CA,
Ayub Q,
Chen Y,
Coffey AJ,
Colonna V,
Huang N,
Jostins L,
Li H,
Scally A,
Walter K,
Xue YL,
Zhang YJ,
Gerstein MB,
Abyzov A,
Balasubramanian S,
Chen JM,
Clarke D,
Fu Y,
Habegger L,
Harmanci AO,
Jin MK,
Khurana E,
Mu XJ,
Sisu C,
Degenhardt J,
Stutz AM,
Church D,
Michaelson JJ,
Ben B,
Lindsay SJ,
Ning ZM,
Yu FL,
Frankish A,
Harrow J,
Fowler G,
Hale W,
Kalra D,
Guo X,
Li G,
Zheng X,
Barker J,
Kelman G,
Kulesha E,
Radhakrishnan R,
Roa A,
Smirnov D,
Streeter I,
Toneva I,
Vaughan B,
Ananiev V,
Belaia Z,
Beloslyudtsev D,
Bouk N,
Chen C,
Cohen R,
Cook C,
Garner J,
Hefferon T,
Kimelman M,
Liu C,
Lopez J,
Meric P,
OSullivan C,
Ostapchuk Y,
Phan L,
Ponomarov S,
Schneider V,
Shekhtman E,
Sirotkin K,
Slotta D,
Zhang H,
Barnes KC,
Beiswanger C,
Cai HY,
Cao HZ,
Gharani N,
Henn B,
Jones D,
Kaye JS,
Kent A,
Kerasidou A,
Mathias R,
Ossorio PN,
Parker M,
Reich D,
Rotimi CN,
Royal CD,
Sandoval K,
Su YY,
Tian ZM,
Tishkoff S,
Toji LH,
Via M,
Wang YH,
Yang HM,
Yang L,
Zhu JY,
Bodmer W,
Bedoya G,
Ming CZ,
Yang G,
You CJ,
Peltonen L,
Garcia-Montero A,
Orfao A,
Dutil J,
Martinez-Cruzado JC,
Brooks LD,
Felsenfeld AL,
McEwen JE,
Clemm NC,
Duncanson A,
Dunn M,
Guyer MS,
Peterson JL,
Genomes Project C

Nature
  491 (7422): 56-65; Nov 1 2012  
[Abstract]
[DOI] [Full Text]

Control of the senescence-associated secretory phenotype by NF-{kappa}B promotes senescence and enhances chemosensitivity
Chien Y,
Scuoppo C,
Wang X,
Fang X,
Balgley B,
Bolden JE,
Premsrirut P,
Luo W,
Chicas A,
Lee CS,
Kogan SC,
Lowe SW

Genes Dev
  25 (20): 2125-2136; Oct 15 2011   NLM
[Abstract]
[DOI]

Clustering of spatial gene expression patterns in the mouse brain and comparison with classical neuroanatomy
Bohland JW,
Bokil H,
Pathak SD,
Lee CK,
Ng L,
Lau C,
Kuan C,
Hawrylycz M,
Mitra PP

Methods
  50 (2): 105-112; Feb 2010   PMC2815007
[Abstract]
[DOI] [Full Text] [PDF]

In Vivo shRNA to Study the Molecular Mechanisms of Radiation Response of Primary Cancers in Mice
Ghafoori A,
Lee C,
Perez B,
Johnston S,
Rodrigues R,
Badea C,
Kim Y,
Lowe SW,
Kirsch DG

International Journal of Radiation Oncology Biology Physics
  75 (3): S171-S172; 2009  
[Full Text]

Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells
Lou Y,
Chen Y,
Hsu S,
Chen R,
Lee C,
Khoo K,
Tonks NK,
Meng T

FEBS Journal
  275 (1): 69-88; Jan 2008  
[Abstract]
[DOI] [Full Text] [PDF]

A second generation human haplotype map of over 3.1 million SNPs
Frazer KA,
Ballinger DG,
Cox DR,
Hinds DA,
Stuve LL,
Gibbs RA,
Belmont JW,
Boudreau A,
Hardenbol P,
Leal SM,
Pasternak S,
Wheeler DA,
Willis TD,
Yu FL,
Yang HM,
Zeng CQ,
Gao Y,
Hu HR,
Hu WT,
Li CH,
Lin W,
Liu SQ,
Pan H,
Tang XL,
Wang J,
Wang W,
Yu J,
Zhang B,
Zhang QR,
Zhao HB,
Zhao H,
Zhou J,
Gabriel SB,
Barry R,
Blumenstiel B,
Camargo A,
Defelice M,
Faggart M,
Goyette M,
Gupta S,
Moore J,
Nguyen H,
Onofrio RC,
Parkin M,
Roy J,
Stahl E,
Winchester E,
Ziaugra L,
Altshuler D,
Shen Y,
Yao ZJ,
Huang W,
Chu X,
He YG,
Jin L,
Liu YF,
Shen YY,
Sun WW,
Wang HF,
Wang Y,
Xiong XY,
Xu L,
Waye MM,
Tsui SK,
Wong JT,
Galver LM,
Fan JB,
Gunderson K,
Murray SS,
Oliphant AR,
Chee MS,
Montpetit A,
Chagnon F,
Ferretti V,
Leboeuf M,
Olivier JF,
Phillips MS,
Roumy S,
Sallee C,
Verner A,
Hudson TJ,
Kwok PY,
Cai DM,
Koboldt DC,
Miller RD,
Pawlikowska L,
Taillon-Miller P,
Xiao M,
Tsui LC,
Mak W,
Song YQ,
Tam PK,
Nakamura Y,
Kawaguchi T,
Kitamoto T,
Morizono T,
Nagashima A,
Ohnishi Y,
Sekine A,
Tanaka T,
Tsunoda T,
Deloukas P,
Bird CP,
Delgado M,
Dermitzakis ET,
Gwilliam R,
Hunt S,
Morrison J,
Powell D,
Stranger BE,
Whittaker P,
Bentley DR,
Daly MJ,
de Bakker PI,
Barrett J,
Chretien YR,
Maller J,
McCarroll S,
Patterson N,
Peer I,
Price A,
Purcell S,
Richter DJ,
Sabeti P,
Saxena R,
Schaffner SF,
Sham PC,
Varilly P,
Stein LD,
Krishnan L,
Smith AV,
Tello-Ruiz MK,
Thorisson GA,
Chakravarti A,
Chen PE,
Cutler DJ,
Kashuk CS,
Lin S,
Abecasis GR,
Guan WH,
Li Y,
Munro HM,
Qin ZH,
Thomas DJ,
McVean G,
Auton A,
Bottolo L,
Cardin N,
Eyheramendy S,
Freeman C,
Marchini J,
Myers S,
Spencer C,
Stephens M,
Donnelly P,
Cardon LR,
Clarke G,
Evans DM,
Morris AP,
Weir BS,
Johnson TA,
Mullikin JC

Nature
  449 (7164): 851-U3; Oct 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Completing the map of human genetic variation
Eichler EE,
Nickerson DA,
Altshuler D,
Bowcock AM,
Brooks LD,
Carter NP,
Church DM,
Felsenfeld A,
Guyer M,
Lee C,
Lupski JR,
Mullikin JC,
Pritchard JK,
Sebat J,
Sherry ST,
Smith D,
Valle D,
Waterston RH

Nature
  447 (7141): 161-165; May 2007  
[DOI] [Full Text] [PDF]

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
Birney E,
Stamatoyannopoulos JA,
Dutta A,
Guigó R,
Gingeras TR,
Margulies EH,
Weng Z,
Snyder M,
Dermitzakis ET,
Thurman RE,
Kuehn MS,
Taylor CM,
Neph S,
Koch CM,
Asthana S,
Malhotra A,
Adzhubei I,
Greenbaum JA,
Andrews RM,
Flicek P,
Boyle PJ,
Cao H,
Carter NP,
Clelland GK,
Davis S,
Day N,
Dhami P,
Dillon SC,
Dorschner MO,
Fiegler H,
Giresi PG,
Goldy J,
Hawrylycz M,
Haydock A,
Humbert R,
James KD,
Johnson BE,
Johnson EM,
Frum TT,
Rosenzweig ER,
Karnani N,
Lee K,
Lefebvre GC,
Navas PA,
Neri F,
Parker SC,
Sabo PJ,
Sandstrom R,
Shafer A,
Vetrie D,
Weaver M,
Wilcox S,
Yu M,
Collins FS,
Dekker J,
Lieb JD,
Tullius TD,
Crawford GE,
Sunyaev S,
Noble WS,
Dunham I,
Denoeud F,
Reymond A,
Kapranov P,
Rozowsky J,
Zheng D,
Castelo R,
Frankish A,
Harrow J,
Ghosh S,
Sandelin A,
Hofacker IL,
Baertsch R,
Keefe D,
Dike S,
Cheng J,
Hirsch HA,
Sekinger EA,
Lagarde J,
Abril JF,
Shahab A,
Flamm C,
Fried C,
Hackermüller J,
Hertel J,
Lindemeyer M,
Missal K,
Tanzer A,
Washietl S,
Korbel J,
Emanuelsson O,
Pedersen JS,
Holroyd N,
Taylor R,
Swarbreck D,
Matthews N,
Dickson MC,
Thomas DJ,
Weirauch MT,
Gilbert J,
Drenkow J,
Bell I,
Zhao X,
Srinivasan KG,
Sung WK,
Ooi HS,
Chiu KP,
Foissac S,
Alioto T,
Brent M,
Pachter L,
Tress ML,
Valencia A,
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Choo CY,
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Bickel P,
Mattick JS,
Carninci P,
Hayashizaki Y,
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Myers RM,
Rogers J,
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Dewey CN,
Hou M,
Nikolaev S,
Montoya-Burgos JI,
Löytynoja A,
Whelan S,
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Huang H,
Zhang NR,
Holmes I,
Mullikin JC,
Ureta-Vidal A,
Paten B,
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Church D,
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Kent WJ,
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Nature
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Temporal profile of replication of human chromosomes
Jeon Y,
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Proceedings of the National Academy of Sciences of the United States of America
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[Abstract]
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The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics
Stein LD,
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PLoS Biol
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Initial sequencing and comparative analysis of the mouse genome
Waterston RH,
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Nature
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[Abstract]
[Full Text]

Effects of pancreatic spasmolytic Polypeptide (PSP) on epithelial cell function
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Eur J Biochem
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[Abstract]
[DOI] [Full Text]

Cloning and Expression of a Mammalian Peptide-Chain Release Factor with Sequence Similarity to Tryptophanyl-Transfer Rna-Synthetases
Lee CC,
Craigen WJ,
Muzny DM,
Harlow E,
Caskey CT

Proceedings of the National Academy of Sciences of the United States of America
  87 (9): 3508-3512; May 1990  
[Full Text]

Actions of dendrotoxin on K+ channels and neuromuscular transmission in Drosophila melanogaster, and its effects in synergy with K+ channel-specific drugs and mutations
Wu CF,
Tsai MC,
Chen ML,
Zhong Y,
Singh S,
Lee CY

J Exp Biol
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[Abstract]
[Full Text] [PDF]

Cloning and characterization of the genes encoding the MspI restriction modification system
Lin PM,
Lee CH,
Roberts RJ

Nucleic Acids Res
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[Abstract]
[Full Text]

Purification of Calmodulin-Stimulated Phosphodiesterase by Affinity-Chromatography on Calmodulin Fragment-1-77 Linked to Sepharose
Draetta G,
Klee CB

Methods in Enzymology
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[Full Text]

Sequence Analyses of Escherichia-Coli Type Ii Heat Stable Entero Toxin Gene
Lee CH,
So M,
Moseley SL,
Moon HW,
Gyles CL

Abstracts of the Annual Meeting of the American Society for Microbiology
  (0): B47; 1983  


Identification of a Transposon-Tn3 Sequence Required for Transposition Immunity
Lee CH,
Bhagwat A,
Heffron F

Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences
  80 (22): 6765-6769; 1983  
[Full Text]

Nature of Transposition Immunity
Heffron F,
Lee C,
Bhagwat A,
McCormick M,
Ohtsubo E

Journal of Cellular Biochemistry - Supplement.(7 PART B)
  (0): 83; 1983  



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