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10 Article(s) on File
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Importance of the N-distal AP-2 binding element in Nef for simian immunodeficiency virus replication and pathogenicity in rhesus macaques
Brenner M,
Münch J,
Schindler M,
Wildum S,
Stolte N,
Stahl-Hennig C,
Fuchs D,
Mätz-Rensing K,
Franz M,
Heeney JL,
Ten Haaft P,
Swigut T,
Hrecka K,
Skowronski J,
Kirchhoff F

Journal of Virology
  80 (9): 4469-4481; May 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Comprehensive analysis of Nef functions selected in simian immunodeficiency virus-infected macaques
Schindler M,
Munch J,
Brenner M,
Stahl-Hennig C,
Skowronski J,
Kirchhoff F

Journal of Virology
  78 (19): 10588-10597; Oct 2004  
[Abstract]
[Full Text]

T-Cell Receptor : CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques
Munch J,
Janardhan A,
Stolte N,
Stahl-Hennig C,
ten Haaft P,
Heeney JL,
Swigut T,
Kirchhoff F,
Skowronski J

Journal of Virology
  76 (23): 12360-12364; Dec 2002  
[Full Text]

Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS
Carl S,
Greenough TC,
Krumbiegel M,
Greenberg M,
Skowronski J,
Sullivan JL,
Kirchhoff F

Journal of Virology
  75 (8): 3657-3665; Apr 2001  
[Abstract]
[Full Text]

Disrupting surfaces of Nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo
Iafrate AJ,
Carl S,
Bronson S,
Stahl-Hennig C,
Swigut T,
Skowronski J,
Kirchhoff F

Journal of Virology
  74 (21): 9836-9844; Nov 2000  
[Abstract]
[Full Text] [PDF]

Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression
Swigut T,
Iafrate AJ,
Muench J,
Kirchhoff F,
Skowronski J

Journal of Virology
  74 (12): 5691-5701; Jun 2000  
[Abstract]
[Full Text]

Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques
Carl S,
Iafrate AJ,
Lang SM,
Stolte N,
Stahl-Hennig C,
Matz-Rensing K,
Fuchs D,
Skowronski J,
Kirchhoff F

Journal of Virology
  74 (9): 4155-4164; May 2000  
[Abstract]
[Full Text]

Partial repair of defective NEF genes in a long-term nonprogressor with human immunodeficiency virus type 1 infection
Carl S,
Daniels R,
Iafrate AJ,
Easterbrook P,
Greenough TC,
Skowronski J,
Kirchhoff F

Journal of Infectious Diseases
  181 (1): 132-140; Jan 2000  
[Abstract]
[Full Text]

Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis
Lock M,
Greenberg ME,
Iafrate AJ,
Swigut T,
Muench J,
Kirchhoff F,
Shohdy N,
Skowronski J

Embo J
  18 (10): 2722-33; May 17 1999  
[Abstract]
[Full Text]

High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection
Mariani R,
Kirchhoff F,
Greenough TC,
Sullivan JL,
Desrosiers RC,
Skowronski J

J Virol
  70 (11): 7752-64; Nov 1996  
[Abstract]
[Full Text]


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