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6 Article(s) on File
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The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence
Wall M,
Poortinga G,
Stanley KL,
Lindemann RK,
Bots M,
Chan CJ,
Bywater MJ,
Kinross KM,
Astle MV,
Waldeck K,
Hannan KM,
Shortt J,
Smyth MJ,
Lowe SW,
Hannan RD,
Pearson RB,
Johnstone RW,
McArthur GA

Cancer Discovery
  3 (1): 82-95; Jan 2013  
[DOI] [Full Text]

Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias
Hein N,
Bywater MJ,
Stanley K,
Verbrugge I,
Cullinane C,
Baker A,
Zuber H,
Rappaport A,
Drygin D,
Huser N,
Bliesath J,
Ryckman DM,
Rice WG,
Lowe SW,
Johnstone RW,
Pearson RB,
McArthur GA,
Hannan RD

Blood
  118 (21): 673-673; Nov 2011  
[Full Text]

The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy
Ellis L,
Bots M,
Lindemann RK,
Bolden JE,
Newbold A,
Cluse LA,
Scott CL,
Strasser A,
Atadja P,
Lowe SW,
Johnstone RW

Blood
  114 (2): 380-393; Jul 9 2009  
[Abstract]
[DOI] [Full Text] [PDF]

Characterization of the apoptotic and therapeutic activities of the histone deacetylase inhibitors LAQ824 and LBH589 using a mouse model of B cell lymphoma
Ellis L,
Lindemann R,
Newbold A,
Whitecross K,
Cluse L,
Pelligrini M,
Wei A,
Scott C,
Atadja P,
Lowe SW,
Johnstone RW

Molecular Cancer Therapeutics
  6 (12): 3475S-3476S; Dec 2007  
[Full Text]

Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma
Lindemann RK,
Newbold A,
Whitecross KF,
Cluse LA,
Frew AJ,
Ellis L,
Williams S,
Wiegmans AP,
Dear AE,
Scott CL,
Pellegrini M,
Wei A,
Richon VM,
Marks PA,
Lowe SW,
Smyth MJ,
Johnstone RW

Proc Natl Acad Sci U S A
  104 (19): 8071-6; May 8 2007  
[Abstract]
[Full Text] [PDF]

Apoptosis: A link between cancer genetics and chemotherapy
Johnstone RW,
Ruefli AA,
Lowe SW

Cell
  108 (2): 153-164; Jan 2002  
[Full Text]


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