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10 Article(s) on File
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Pharmacology of a central nervous system delivered 2′-O-methoxyethyl- modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates
Rigo F,
Chun SJ,
Norris DA,
Hung G,
Lee S,
Matson J,
Fey RA,
Gaus H,
Hua Y,
Grundy JS,
Krainer AR,
Henry SP,
Bennett CF

Journal of Pharmacology and Experimental Therapeutics
  350 (1): 46-55; Jul 2014 2014   NLM
[Abstract]
[DOI] [Full Text]

Pathological impact of SMN2 mis-splicing in adult SMA mice
Sahashi K,
Ling KK,
Hua Y,
Wilkinson JE,
Nomakuchi T,
Rigo F,
Hung G,
Xu D,
Jiang YP,
Lin RZ,
Ko CP,
Bennett CF,
Krainer AR

EMBO Mol Med
  5 (10): 1586-601; Oct 2013   NLM
[Abstract]
[DOI] [Full Text]

Pathological impact of SMN2 mis-splicing in adult SMA mice
Sahashi K,
Ling KK,
Hua Y,
Wilkinson JE,
Nomakuchi T,
Rigo F,
Hung G,
Xu D,
Jiang YP,
Lin RZ,
Ko CP,
Bennett CF,
Krainer AR

EMBO Mol Med
  5 (10): 1586-1601; Sep 9 2013   NLM
[Abstract]
[DOI] [Full Text]

The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model
Gutschner T,
Hammerle M,
Eissmann M,
Hsu J,
Kim Y,
Hung GN,
Revenko A,
Arun G,
Stentrup M,
Gross M,
Zornig M,
MacLeod AR,
Spector DL,
Diederichs S

Cancer Research
  73 (8): 1121; Apr 2013  
[Abstract]
[DOI] [Full Text]

The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells
Gutschner T,
Hämmerle M,
Eißmann M,
Hsu J,
Kim Y,
Hung G,
Revenko A,
Arun G,
Stentrup M,
Groß M,
Zörnig M,
MacLeod AR,
Spector DL,
Diederichs S

Cancer Research
  73 (3): 1180-1189; Feb 2013  
[Abstract]
[DOI] [Full Text]

TSUNAMI: an antisense method to phenocopy splicing-associated diseases in animals
Sahashi K,
Hua Y,
Ling KK,
Hung G,
Rigo F,
Horev G,
Katsuno M,
Sobue G,
Ko CP,
Bennett CF,
Krainer AR

Genes Dev
  26 (16): 1874-84; Aug 15 2012   NLM
[Abstract]
[DOI] [Full Text]

The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult
Zhang B,
Arun G,
Mao Y,
Lazar Z,
Hung G,
Bhattacharjee G,
Xiao X,
Booth C,
Wu J,
Zhang C,
Spector D

Cell Reports
  2 (1): 111-123; Jul 26 2012  
[Abstract]
[DOI] [Full Text]

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
Hua Y,
Sahashi K,
Rigo F,
Hung G,
Horev G,
Bennett CF,
Krainer AR

Nature
  478 (7367): 123-6; Oct 6 2011   NLM
[Abstract]
[DOI] [Full Text]

Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy
Passini MA,
Bu J,
Richards AM,
Kinnecom C,
Sardi SP,
Stanek LM,
Hua ,
Rigo F,
Matson J,
Hung G,
Kaye EM,
Shihabuddin LS,
Krainer AR,
Bennett CF,
Cheng SH

Science Translational Medicine
  3 (72): Mar 2 2011   Elsevier PMC3140425
[Abstract]
[DOI]

Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
Hua Y,
Sahashi K,
Hung G,
Rigo F,
Passini MA,
Bennett CF,
Krainer AR

Genes Dev
  24 (15): 1634-44; Aug 1 2010   PMCID: PMC2912561
[Abstract]
[DOI] [Full Text] [PDF]


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