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71 Article(s) on File
Page 1 of 1
The Cancer Stem Cell: Cell Type or Cell State?
Donnenberg AD,
Hicks JB,
Wigler M,
Donnenberg VS

Cytometry Part A
  83A (0): 5-7; Jan 2013  
[DOI] [Full Text]

Genome-wide copy number analysis of single cells
Baslan T,
Kendall JT,
Rodgers L,
Cox H,
Riggs M,
Stepansky A,
Troge JE,
Ravi K,
Esposito D,
Lakshmi B,
Wigler M,
Navin NE,
Hicks JB

Nat Protoc
  7 (6): 1024-41; May 3 2012   Nlm
[Abstract]
[DOI] [Full Text]

Human epidermal growth factor receptor 2 testing in gastroesophageal cancer: Correlation between immunohistochemistry and fluorescence in situ hybridization
Tafe LJ,
Janjigian YY,
Zaidinski M,
Hedvat CV,
Hameed MR,
Tang LH,
Hicks JB,
Shah MA,
Barbashina V

Archives of Pathology and Laboratory Medicine
  135 (11): 1460-1465; Nov 2011  
[Abstract]
[DOI] [Full Text]

BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity
Shakya R,
Reid LJ,
Reczek CR,
Cole F,
Egli D,
Lin CS,
DeRooij DG,
Hirsch S,
Ravi K,
Hicks JB,
Szabolcs M,
Jasin M,
Baer R,
Ludwig T

Science
  334 (6055): 525-528; Oct 28 2011  
[Abstract]
[DOI] [Full Text]

Insight into the heterogeneity of breast cancer through next-generation sequencing
Russnes HG,
Navin N,
Hicks JB,
Borresen-Dale AL

Journal of Clinical Investigation
  121 (10): 3810-3818; Oct 2011   PMC3195464
[Abstract]
[DOI] [Full Text]

Corrigendum to Tracing the tumor lineage [Mol. Oncol. 4 (2010) 267-283]
Navin NE,
Hicks JB

Molecular Oncology
  5 (3): 302; Jun 11 2011   Elsevier
[DOI]

Future medical applications of single-cell sequencing in cancer
Navin N,
Hicks JB

Genome Medicine
  3 (5): May 31 2011  
[Abstract]
[DOI] [Full Text]

MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer
Png KJ,
Yoshida M,
Zhang XH,
Shu W,
Lee H,
Rimner A,
Chan TA,
Comen E,
Andrade VP,
Kim SW,
King TA,
Hudis CA,
Norton L,
Hicks JB,
Massagué J,
Tavazoie SF

Genes and Development
  25 (3): 226-231; Feb 1 2011   Elsevier PMC3034897
[Abstract]
[DOI]

DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables
Kamalakaran S,
Varadan V,
Giercksky Russnes HE,
Levy D,
Kendall JT,
Janevski A,
Riggs M,
Banerjee N,
Synnestvedt M,
Schlichting E,
KÃ¥resen R,
Shama Prasada K,
Rotti H,
Rao R,
Rao L,
Eric Tang MH,
Satyamoorthy K,
Lucito R,
Wigler MH,
Dimitrova N,
Naume B,
Borresen-Dale AL,
Hicks JB

Molecular Oncology
  5 (1): 77-92; Feb 2011  
[Abstract]
[DOI] [Full Text] [PDF]

Tumour evolution inferred by single-cell sequencing
Navin NE,
Kendall JT,
Troge JE,
Andrews P,
Rodgers ,
McIndoo J,
Cook K,
Stepansky ,
Levy D,
Esposito D,
Muthuswamy L,
Krasnitz A,
McCombie WR,
Hicks JB,
Wigler MH

Nature
  (0): 2011   Elsevier
[Abstract]
[DOI] [Full Text]

Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
Russnes HG,
Vollan HK,
Lingjærde OC,
Krasnitz A,
Lundin P,
Naume B,
Sørlie T,
Borgen E,
Rye IH,
Langerød A,
Chin SF,
Teschendorff AE,
Stephens PJ,
Månér S,
Schlichting E,
Baumbusch LO,
Kåresen R,
Stratton MP,
Wigler MH,
Caldas C,
Zetterberg A,
Hicks JB,
Børresen-Dale AL

Science Translational Medicine
  2 (38): Jun 30 2010  
[Abstract]
[DOI] [Full Text] [PDF]

Tracing the tumor lineage
Navin NE,
Hicks JB

Molecular Oncology
  (0): May 5 2010   PMCID: PMC2904844
[Abstract]
[DOI] [Full Text] [PDF]

Tracing Tumor Lineage and Progression through Genomic Copy Number Profiling at the Single Cell Level
Hicks JB,
Navin NE,
Kendall JT,
Levy D,
Wigler MH

Annals of Oncology
  21 (0): 96O; May 2010  
[Full Text]

A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding
Floer M,
Wang X,
Prabhu V,
Berrozpe G,
Narayan S,
Spagna D,
Alvarez D,
Kendall JT,
Krasnitz A,
Stepansky ,
Hicks JB,
Bryant GO,
Ptashne M

Cell
  141 (3): 407-418; Apr 29 2010   PMCID: PMC3032599
[Abstract]
[DOI] [Full Text] [PDF]

Inferring tumor progression from genomic heterogeneity
Navin NE,
Krasnitz A,
Rodgers L,
Cook K,
Meth JL,
Kendall JT,
Riggs M,
Eberling Y,
Troge JE,
Grubor V,
Levy D,
Lundin P,
Månér S,
Zetterberg A,
Hicks JB,
Wigler MH

Genome Research
  20 (1): 68-80; Jan 2010   PMCID: PMC2798832
[Abstract]
[DOI] [Full Text] [PDF]

Updates to the RMAP short-read mapping software
Smith AD,
Chung WY,
Hodges E,
Kendall JT,
Hannon GJ,
Hicks JB,
Xuan Z,
Zhang MQ

Bioinformatics
  25 (21): 2841-2842; Nov 1 2009   PMCID: PMC2895571
[Abstract]
[DOI] [Full Text] [PDF]

Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model
Bric A,
Miething C,
Bialucha CU,
Scuoppo C,
Zender L,
Krasnitz A,
Xuan Z,
Zuber J,
Wigler MH,
Hicks JB,
McCombie RW,
Hemann MT,
Hannon GJ,
Powers S,
Lowe SW

Cancer Cell
  16 (4): 324-35; Oct 6 2009   PMC2829755
[Abstract]
[DOI] [Full Text] [PDF]

High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing Dup removed 04/2012
Hodges E,
Smith AD,
Kendall JT,
Xuan Z,
Ravi K,
Rooks M,
Zhang MQ,
Ye K,
Bhattacharjee A,
Brizuela L,
McCombie WR,
Wigler MH,
Hannon GJ,
Hicks JB

Genome Res
  19 (9): 1593-1605; Sep 2009   PMCID: PMC2752124
[Abstract]
[DOI] [Full Text] [PDF]

High resolution microarray copy number analysis (array CGH) suggests that determination of HER2 amplification by FISH (FISH plus ) is inaccurate in human breast cancer specimens that are HER2 2+by immunohistochemistry (IHC2+)
McArthur HL,
Brogi E,
Patil S,
Wigler MH,
Norton L,
Hicks JB,
Hudis CA

Ejc Supplements
  7 (2): 88-88; Sep 2009  
[DOI] [Full Text] [PDF]

Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
Kamalakaran S,
Kendall JT,
Zhao X,
Tang C,
Khan S,
Ravi K,
Auletta T,
Riggs M,
Wang Y,
Helland A,
Naume B,
Dimitrova N,
Borresen-Dale AL,
Hicks JB,
Lucito R

Nucl. Acids Res.
  37 (12): e89; Jul 2009   PMCID: PMC2709589
[Abstract]
[DOI] [Full Text] [PDF]

Topo2a and Her2 Co-Amplification Is Uncommon by High Resolution Representational Oligonucleotide Microarray Analysis (Roma) in Human Breast Cancer
Hicks JB,
McArthur H,
Tan LK,
Patil S,
Wigler MH,
Hudis C,
Norton L

Annals of Oncology
  20 (0): 22-23; May 2009  
[Full Text]

Molecular subclassification of breast carcinomas based on aCGH reveals two major groups of tumors with common genomic, transcriptomic and clinicopathological characteristics
Russnes HG,
Vollan HK,
Sorlie T,
Krasnitz A,
Zetterberg A,
Naume B,
Borgen E,
Nesland JM,
Wigler MH,
Borresen-Dale AL,
Hicks JB

Apmis
  117 (3): 238-239; Mar 2009  
[Full Text]

High resolution representational oligonucleotide microarray analysis (ROMA) suggests that TOPO2 and HER2 co-amplification is uncommon in human breast cancer
McArthur HL,
Tan LK,
Patil S,
Wigler MH,
Hudis CA,
Hicks JB,
Norton L

Cancer Res
  69 (2): 163S-163S; Jan 15 2009  
[DOI] [Full Text]

An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer
Zender L,
Xue W,
Zuber J,
Semighini CP,
Krasnitz A,
Ma B,
Zender P,
Kubicka S,
Luk JM,
Schirmacher P,
McCombie WR,
Wigler MH,
Hicks JB,
Hannon GJ,
Powers S,
Lowe SW

Cell
  135 (5): 852-864; Nov 28 2008   PMC2990916
[Abstract]
[DOI] [Full Text] [PDF]

Brk is coamplified with ErbB2 to promote proliferation in breast cancer
Xiang B,
Chatti K,
Qiu H,
Lakshmi B,
Krasnitz A,
Hicks JB,
Yu M,
Miller WT,
Muthuswamy SK

Proc Natl Acad Sci U S A
  105 (34): 12463-8; Aug 26 2008   PMCID: PMC2527934
[Abstract]
[DOI] [Full Text] [PDF]

Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors
Baumbusch LO,
Aaroe J,
Johansen FE,
Hicks JB,
Sun H,
Bruhn L,
Gunderson K,
Naume B,
Kristensen VN,
Liestol K,
Borresen-Dale AL,
Lingjaerde OC

BMC Genomics
  9 (0): 379; Aug 2008   PMCID: PMC2547478
[Abstract]
[DOI] [Full Text] [PDF]

Molecular subclassification of breast carcinomas based on aCGH, gene expression, IHC and ploidy - relevance for clinical outcome
Russnes HG,
Sorlie T,
Krasnitz A,
Zetterberg A,
Naume B,
Borgen E,
Nesland JM,
Wigler MH,
Borresen-Dale AL,
Hicks JB

Ejc Supplements
  6 (9): 9-9; Jul 2008  
[DOI]

No genomic changes in mammographically dense breast
Haakensen VD,
Helland A,
Holmen MM,
Hicks JB,
Børresen-Dale AL

Ejc Supplements
  5 (4): 99-99; Sep 2007  
[DOI] [PDF]

Strong Association of De Novo Copy Number Mutations with Autism
Sebat J,
Lakshmi B,
Malhotra D,
Troge JE,
Lese-Martin C,
Walsh T,
Yamrom B,
Yoon S,
Krasnitz A,
Kendall JT,
Leotta A,
Pai D,
Zhang R,
Lee YH,
Hicks JB,
Spence SJ,
Lee AT,
Puura K,
Lehtimaki T,
Ledbetter D,
Gregersen PK,
Bregman J,
Sutcliffe JS,
Jobanputra V,
Chung W,
Warburton D,
King MC,
Skuse D,
Geschwind DH,
Gilliam TC,
Ye K,
Wigler MH

Science
  316 (5823): 445-449; April 20 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Identification of alterations in DNA copy number in host stromal cells during tumor progression
Pelham RJ,
Rodgers L,
Hall IM,
Lucito R,
Nguyen KC,
Navin NE,
Hicks JB,
Mu D,
Powers S,
Wigler MH,
Botstein D

Proc Natl Acad Sci U S A
  103 (52): 19848-19853; Dec 2006  
[Abstract]
[DOI] [Full Text]

Novel patterns of genome rearrangement and their association with survival in breast cancer
Hicks JB,
Krasnitz A,
Lakshmi B,
Navin NE,
Riggs M,
Leibu E,
Esposito D,
Alexander J,
Troge JE,
Grubor V,
Yoon S,
Wigler MH,
Ye K,
Borresen-Dale AL,
Naume B,
Schlicting E,
Norton L,
Hagerstrom T,
Skoog L,
Auer G,
Månér S,
Lundin P,
Zetterberg A

Genome Res
  16 (12): 1465-79; Dec 2006  
[Abstract]
[DOI] [Full Text] [PDF]

High-resolution ROMA CGH and FISH analysis of aneuploid and diploid breast tumors
Hicks JB,
Muthuswamy L,
Krasnitz A,
Navin NE,
Riggs M,
Grubor V,
Esposito D,
Alexander J,
Troge JE,
Wigler MH,
Maner S,
Lundin P,
Zetterberg A

Cold Spring Harbor Symposia on Quantitative Biology VXX: Molecular approaches to controlling cancer
  70 51-63; 2005  
[Abstract]
[DOI] [Full Text]

Large-scale copy number polymorphism in the human genome
Sebat J,
Lakshmi B,
Troge JE,
Alexander J,
Young J,
Lundin P,
Maner S,
Massa H,
Walker M,
Chi M,
Navin NE,
Lucito R,
Healy J,
Hicks JB,
Ye K,
Reiner A,
Gilliam TC,
Trask B,
Patterson N,
Zetterberg A,
Wigler MH

Science
  305 (5683): 525-8; Jul 23 2004  
[Abstract]
[DOI] [Full Text]

The Sir1 Gene of Saccharomyces-Cerevisiae and Its Role as an Extragenic Suppressor of Several Mating-Defective Mutants
Stone EM,
Swanson MJ,
Romeo AM,
Hicks JB,
Sternglanz R

Molecular and Cellular Biology
  11 (4): 2253-2262; Apr 1991  
[Abstract]
[Full Text]

The sum1-1 mutation affects silent mating-type gene transcription in Saccharomyces cerevisiae
Livi GP,
Hicks JB,
Klar AJ

Molecular Cellular Biology
  10 (1): 409-12; Jan 1990  
[Abstract]
[Full Text]

High-frequency switching in Candida strains isolated from vaginitis patients
Soll DR,
Langtimm CJ,
McDowell J,
Hicks JB,
Galask R

J Clin Microbiol
  25 (9): 1611-22; Sep 1987   NLM
[Abstract]
[Full Text]

Mechanisms of differentiation
Hicks JB

Nature
  326 (6112): 444-445; 1987  
[Full Text]

Cloning and Characterization of 4 Sir Genes of Saccharomyces-Cerevisiae
Ivy JM,
Klar AJ,
Hicks JB

Molecular and Cellular Biology
  6 (2): 688-702; Feb 1986  
[Full Text]

Sum1, an Apparent Positive Regulator of the Cryptic Mating-Type Loci in Saccharomyces-Cerevisiae
Klar AJ,
Kakar SN,
Ivy JM,
Hicks JB,
Livi GP,
Miglio LM

Genetics
  111 (4): 745-758; 1985  
[Full Text]

Map Positions of Yeast Genes Sir1, Sir3 and Sir4
Ivy JM,
Hicks JB,
Klar AJ

Genetics
  111 (4): 735-744; 1985  
[Full Text]

Initiation and Resolution of Mating Type Switching in Yeast
Strathern J,
Klar AJ,
McGill C,
Abraham J,
Weisbrod ST,
Kelly M,
Stephens C,
Hicks JB

Journal of Cellular Biochemistry - Supplement.(8 PART B)
  (0): 125; 1984  


Identification of Sites Required for Repression of a Silent Mating Type Locus in Yeast
Feldman JB,
Hicks JB,
Broach JR

Journal of Molecular Biology
  178 (4): 815-834; 1984  
[Full Text]

Spontaneous Mutations in Maize Associated with Viral Infection
Dellaporta SL,
Mottinger JP,
Hicks JB

Journal of Cellular Biochemistry - Supplement.(8 PART B)
  (0): 224; 1984  


Endogenous Transposable Elements Associated with Virus Infection in Maize
Dellaporta SL,
Chomet PS,
Mottinger JP,
Wood JA,
Yu SM,
Hicks JB

Cold Spring Harbor Symposia on Quantitative Biology XLIX: Recombination at the DNA Level
  49 321-328; 1984  


Regulation of Mating-Type Information in Yeast - Negative Control Requiring Sequences Both 5 and 3 to the Regulated Region
Abraham J,
Nasmyth KA,
Strathern JN,
Klar AJ,
Hicks JB

Journal of Molecular Biology
  176 (3): 307-331; 1984  
[Full Text]

A Site-Specific Endonuclease Essential for Mating-Type Switching in Saccharomyces Cerevisiae
Kostriken R,
Strathern JN,
Klar AJ,
Hicks JB,
Heffron F

Cell
  35 (1): 167-174; 1983  
[Full Text]

Efficient Production of a Ring Derivative of Chromosome-Iii by the Mating-Type Switching Mechanism in Saccharomyces-Cerevisiae
Klar AJ,
Strathern JN,
Hicks JB,
Prudente D

Molecular and Cellular Biology
  3 (5): 803-810; 1983  
[Full Text]

Sad Mutation of Saccharomyces-Cerevisiae Is an Extra a-Cassette
Kassir Y,
Hicks JB,
Herskowitz I

Molecular and Cellular Biology
  3 (5): 871-880; 1983  
[Full Text]

Homothallic Switching of Yeast Mating Type Cassettes Is Initiated by a Double-Stranded Cut in the Mat Locus
Strathern JN,
Klar AJ,
Hicks JB,
Abraham JA,
Ivy JM,
Nasmyth KA,
McGill C

Cell
  31 (1): 183-192; 1982  
[Full Text]

Directionality of Yeast Mating-Type Interconversion
Klar AJ,
Hicks JB,
Strathern JN

Cell
  28 (3): 551-561; 1982  
[Full Text]

Directionality of Yeast Saccharomyces-Cerevisiae Mating Type Inter Conversion
Klar AJ,
Hicks JB,
Strathern JN

Cell
  28 (3): 551-562; 1982  
[Abstract]


Localization and Sequence-Analysis of Yeast Origins of DNA-Replication
Broach JR,
Li YY,
Feldman J,
Jayaram M,
Abraham J,
Nasmyth KA,
Hicks JB

Cold Spring Harbor Symposia on Quantitative Biology XLVII: Structures of DNA
  47 1165-1173; 1982  
[Full Text]

Sites Required for Position-Effect Regulation of Mating-Type Information in Yeast
Abraham J,
Feldman J,
Nasmyth KA,
Strathern JN,
Klar AJ,
Broach JR,
Hicks JB

Cold Spring Harbor Symposia on Quantitative Biology
  47 (0): 989-998; 1982  
[Full Text]

Molecular Details of the Directed DNA Rearrangement That Differentiates Cell Type in Yeast
Strathern JN,
Hicks JB,
Klar AJ,
Nasmyth K

Journal of Supramolecular Structure Cellular Biochemistry.(SUPPL
  5) (0): 399; 1981  


A Position-Effect Control for Gene Transposition - State of Expression of Yeast Mating-Type Genes Affects Their Ability to Switch
Klar AJ,
Strathern JN,
Hicks JB

Cell
  25 (2): 517-524; 1981  
[Full Text]

Regulation of Transcription in Expressed and Unexpressed Mating Type Cassettes of Yeast
Klar AJ,
Strathern JN,
Broach JR,
Hicks JB

Nature
  289 (5795): 239-244; 1981  
[Full Text]

Irregular transpositions of mating-type genes in yeast
Klar AJ,
Hicks JB,
Strathern JN

Cold Spring Harbor Symposia on Quantitative Biology
  45 Pt (0): 983-990; 1981  
[Full Text]

Replication and Recombination Functions Associated with the Yeast Plasmid, 2-Mu Circle
Broach JR,
Hicks JB

Cell
  21 (2): 501-508; Sep 1980  
[Abstract]
[DOI] [Full Text]

Structure and organization of transposable mating type cassettes in Saccharomyces yeasts
Strathern JN,
Spatola E,
McGill C,
Hicks JB

Proceedings of the National Academy of Sciences of the United States of America
  77 (5): 2839-2843; 1980  
[Full Text]

Evidence for a Physical Interaction between the Transposed and the Substituted Sequences During Mating Type Gene Transposition in Yeast
Klar AJ,
McIndoo J,
Strathern JN,
Hicks JB

Cell
  22 (1): 291-298; 1980  
[Abstract]


Precise mapping of the homothallism genes HML and HMR in Saccharomyces cerevisiae
Klar AJ,
McIndoo J,
Hicks JB,
Strathern JN

Genetics
  96 (2): 315-320; 1980  
[Full Text]

Precise Mapping of the Homo Thallism Genes Hml and Hmr in Saccharomyces-Cerevisiae
Klar AJ,
McIndoo J,
Hicks JB,
Strathern JN

Genetics
  96 (2): 315-320; 1980  
[Abstract]


Irregular Transpositions of Mating-Type Genes in Yeast
Klar AJ,
Hicks JB,
Strathern JN

Cold Spring Harbor Symposia on Quantitative Biology
  45 (0): 983-990; 1980  
[Full Text]

Isolation of a circular derivative of yeast chromosome III: Implications for the mechanism of mating type interconversion
Strathern JN,
Newlon CS,
Herskowitz I,
Hicks JB

Cell
  18 (2): 309-319; 1979  
[Full Text]

A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: Evidence for and identification of cryptic mating-type loci
Rine J,
Strathern JN,
Hicks JB,
Herskowitz I

Genetics
  93 (4): 877-901; 1979  
[Full Text]

Transformation in Yeast - Development of a Hybrid Cloning Vector and Isolation of the Can1-Gene
Broach JR,
Strathern JN,
Hicks JB

Gene
  8 (1): 121-133; 1979  
[Full Text]

Transformation of yeast
Hinnen A,
Hicks JB,
Fink GR

Proceedings of the National Academy of Sciences of the United States of America
  75 (4): 1929-1933; 1978  
[Abstract]
[Full Text]

Interconversion of yeast mating types. III. Action of the homothallism (HO) gene in cells homozygous for the mating type locus
Hicks JB,
Strathern JN,
Herskowitz I

Genetics
  85 (3): 395-405; 1977  
[Full Text]

Interconversion of yeast mating types. II. Restoration of mating ability to sterile mutants in homothallic and heterothallic strains
Hicks JB,
Herskowitz I

Genetics
  85 (3): 373-393; 1977  
[Full Text]

Interconversion of Yeast Mating Types I. Direct Observations of the Action of the Homothallism (HO) Gene
Hicks JB,
Herskowitz I

Genetics
  83 (2): 245-58; Jun 1976   NLM
[Abstract]
[Full Text]

Evidence for a new diffusible element of mating pheromones in yeast
Hicks JB,
Herskowitz I

Nature
  260 (5548): 246-248; Mar 18 1976  
[Full Text]


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