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56 Article(s) on File
Page 1 of 1
Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis
Blasco MA,
Rizen M,
Greider CW,
Hanahan D

Nat Genet
  12 (2): 200-4; Feb 1996  
[Abstract]
[Full Text]

Early invasiveness characterizes metastatic carcinoid tumors in transgenic mice
Grant SG,
Seidman I,
Hanahan D,
Bautch VL

Cancer Res
  51 (18): 4917-23; Sep 15 1991  
[Abstract]
[Full Text]

Determinants of the B-cell response against a transgenic autoantigen
Skowronski J,
Jolicoeur C,
Alpert S,
Hanahan D

Proc Natl Acad Sci U S A
  87 (19): 7487-91; Oct 1990  
[Abstract]
[Full Text]

Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants
Grant SG,
Jessee J,
Bloom FR,
Hanahan D

Proc Natl Acad Sci U S A
  87 (12): 4645-9; Jun 1990  
[Abstract]
[Full Text]

Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor
Powers AC,
Efrat S,
Mojsov S,
Spector D,
Habener JF,
Hanahan D

Diabetes
  39 (4): 406-14; Apr 1990  
[Abstract]
[Full Text]

Expression of General Neuroendocrine Markers and Hormones in Pancreatic Glucagonomas of Transgenic Mice
Rindi G,
Efrat S,
Ghatei MA,
Bloom SR,
Solcia E,
Hanahan D,
Polak JM

Journal of Pathology
  160 (2): A154-A154; Feb 1990  
[Full Text]

Plasmid Rescue Using Escherichia-Coli Methylation-Restriction Mutants Allows Efficient Cloning of Transgenic Mouse DNA and Implicates DNA Modifications That Correlate with Developmental Timing of Transgene Expression
Grant S,
Jesse J,
Bloom F,
Hanahan D

Journal of Cellular Biochemistry - Supplement.(14 PART E)
  (0): 158; 1990  


Specific Chromosomal-Abnormalities Characterize Fibrosarcomas of Bovine Papillomavirus Type-1 Transgenic Mice
Lindgren V,
Sippolathiele M,
Skowronski J,
Wetzel E,
Howley PM,
Hanahan D

Proceedings of the National Academy of Sciences of the United States of America
  86 (13): 5025-5029; Jul 1989  
[Full Text]

Directed Expression of Ngf to Pancreatic Beta-Cells in Transgenic Mice Leads to Selective Hyperinnervation of the Islets
Edwards RH,
Rutter WJ,
Hanahan D

Cell
  58 (1): 161-170; Jul 1989  
[Full Text]

Induction of Angiogenesis During the Transition from Hyperplasia to Neoplasia
Folkman J,
Watson K,
Ingber D,
Hanahan D

Nature
  339 (6219): 58-61; May 1989  
[Full Text]

Cell-Heritable Stages of Tumor Progression in Transgenic Mice Harboring the Bovine Papillomavirus Type-1 Genome
Sippolathiele M,
Hanahan D,
Howley PM

Molecular and Cellular Biology
  9 (3): 925-934; Mar 1989  
[Full Text]

Factors Modulating Immunological Non-Responsivenes and Autoimmunity in Insulin T Antigen Transgenic Mice
Skowronski J,
Alpert S,
Hanahan D

Journal of Cellular Biochemistry - Supplement.(13 PART A)
  (0): 286; 1989  


Cdna Sequence of Neuro-Endocrine Protein 7b2 Expressed in Beta-Cell Tumors of Transgenic Mice
Mbikay M,
Grant SG,
Sirois F,
Tadros H,
Skowronski J,
Lazure C,
Seidah NG,
Hanahan D,
Chretien M

International Journal of Peptide and Protein Research
  33 (1): 39-45; Jan 1989  
[Full Text]

Alternative Self or Nonself Recognition of an Antigen Expressed in a Rare Cell Type in Transgenic Mice - Implications for Self-Tolerance and Autoimmunity
Hanahan D,
Jolicoeur C,
Alpert S,
Skowronski J

Cold Spring Harbor Symposia on Quantitative Biology
  54 (0): 821-835; 1989  
[Full Text]

Biologically Pure Escherichia-Coli Cell Line Which Is a Deo-R-Negative Mutant and Which Is More Transformation Efficient with Foreign Plasmids Than Deo-R-Positive Escherichia-Coli Cell Lines Processes for Obtaining These Cell Lines Methods of Use Us Patent-4851348. July 25 1989
Hanahan D

Official Gazette of the United States Patent Trademark Office Patents
  1104 (4): 2669; 1989  


Evidence for Threshold Effects in Transformation of Pancreatic Beta-Cells by Sv40 T-Antigen in Transgenic Mice
Efrat S,
Hanahan D

Current Topics in Microbiology and Immunology
  144 (0): 89-95; 1989  
[Full Text]

Tissue Specificity of Oncogene Action Endothelial Cell Tumors in Polyoma Middle T Transgenic Mice
Bautch VL,
Toda S,
Hassell JA,
Hanahan D
In:
Perinatal and multigeneration carcinogenesis
(eds. Napalkov, N. P. et al.) Lyon, France: Iarc (International ; 1989. 96: 255-266  


Tissue specificity of oncogene action: endothelial cell tumours in polyoma middle T transgenic mice
Bautch VL,
Toda S,
Hassell JA,
Hanahan D

IARC Sci Publ
  (96): 255-66; 1989  
[Abstract]
[Full Text]

Targeted Expression of Viral Genes to Pancreatic Beta Cells in Transgenic Mice
Alpert S,
Hanahan D,
Bautch VL
In:
Concepts in viral pathogenesis III
(eds. Notkins, A. L. Oldstone, M. B. A.) New York: Springer-Verlag; 1989. : 177-186  


Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene
Efrat S,
Linde S,
Kofod H,
Spector D,
Delannoy M,
Grant S,
Hanahan D,
Baekkeskov S

Proc Natl Acad Sci U S A
  85 (23): 9037-41; Dec 1988  
[Abstract]
[DOI] [Full Text] [PDF]

Neonatal Hepatitis Induced by Alpha-1-Antitrypsin - a Transgenic Mouse Model
Dycaico MJ,
Grant SG,
Felts K,
Nichols WS,
Geller SA,
Hager JH,
Pollard AJ,
Kohler SW,
Short HP,
Jirik FR,
Hanahan D,
Sorge JA

Science
  242 (4884): 1409-1412; Dec 1988  
[Full Text]

Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic alpha cells
Efrat S,
Teitelman G,
Anwar M,
Ruggiero D,
Hanahan D

Neuron
  1 (7): 605-13; Sep 1988  
[Abstract]
[Full Text]

Genetic and Maternal Influences in the Development of Autoimmune-Response in Transgenic Mice
Skowronski J,
Alpert S,
Hanahan D

Diabetes
  37 (5): A7-A7; May 1988  
[Full Text]

Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons
Alpert S,
Hanahan D,
Teitelman G

Cell
  53 (2): 295-308; Apr 22 1988  
[Abstract]
[Full Text]

Mcra and Mcrb Restriction Phenotypes of Some Escherichia-Coli Strains and Implications for Gene Cloning
Raleigh EA,
Murray NE,
Revel H,
Blumenthal RM,
Westaway D,
Reith AD,
Rigby PW,
Elhai J,
Hanahan D

Nucleic Acids Research
  16 (4): 1563-1575; Feb 1988  
[Full Text]

Proliferation, Senescence, and Neoplastic Progression of Beta-Cells in Hyperplasic Pancreatic-Islets
Teitelman G,
Alpert S,
Hanahan D

Cell
  52 (1): 97-105; Jan 1988  
[Full Text]

Ultrastructure and Electron Immunocytochemistry of Insulin-Producing B-Cell Tumors from Transgenic Mice - Comparison with Counterpart Human-Tumors
Holm R,
Varndell IM,
Power RF,
Bishop AE,
Madsen OD,
Alpert S,
Hanahan D,
Polak JM

Ultrastructural Pathology
  12 (5): 547-559; 1988  
[Full Text]

Dissecting multistep tumorigenesis in transgenic mice
Hanahan D

Annu Rev Genet
  22 (0): 479-519; 1988  


A Subset of Central and Peripheral Neuronal Precursors Express an Insulin Gene Construct Prior to Commitment in Transgenic Mouse Embryos
Alpert S,
Hanahan D,
Moustakos M,
Teitelman G

Society for Neuroscience Abstracts
  14 (1): 91; 1988  


Endothelial cell tumors develop in transgenic mice carrying polyoma virus middle T oncogene
Bautch VL,
Toda S,
Hassell JA,
Hanahan D

Cell
  51 (4): 529-37; Nov 20 1987  
[Abstract]
[Full Text]

Coordinate expression of the endogenous p53 gene in beta cells of transgenic mice expressing hybrid insulin-SV40 T antigen genes
Efrat S,
Baekkeskov S,
Lane D,
Hanahan D

Embo J
  6 (9): 2699-704; Sep 1987  
[Abstract]
[Full Text]

Expression of the Murine P53 Protein in Beta Cells of Insulin-Sv40 T Antigen Transgenic Mice
Efrat S,
Baekkeskov S,
Lane D,
Hanahan D
In:
Nuclear Oncogenes
(eds. Alt, F. W. Harlow, E. Ziff, E. B.) Cold Spring Harbor, NY: Cold Spring Harbor L; 1987. : 132-137  


Transgenic Mouse Model - a New Approach for the Investigation of Endocrine Pancreatic B-Cell Growth
Power RF,
Holm R,
Bishop AE,
Varndell IM,
Alpert S,
Hanahan D,
Polak JM

Gut
  28 (0): 121-129; 1987  
[Full Text]

Directional Cdna Cloning in Plasmid Vectors by Sequential Addition of Oligonucleotide Linkers
Helfman DM,
Fiddes JC,
Hanahan D

Methods in Enzymology
  152 (0): 349-359; 1987  
[Full Text]

Multiple Skin Pathologies in Transgenic Mice Harboring the Bovine Papilloma Virus Genome
Hanahan D,
Alpert S,
Lacey M
In:
Viral carcinogenesis : functional aspects : proceedings of the Alfred Benzon Symposium 24 held at the premises of the Royal Danish Academy of Sciences and Letters, Copenhagen 15-19 June 1986
(eds. Kjeldgaard, N. O. Forchhammer, J.) New York: Raven Press; 1987. : 263-271  


Bidirectional Activity of the Rat Insulin-Ii 5-Flanking Region in Transgenic Mice
Efrat S,
Hanahan D

Molecular and Cellular Biology
  7 (1): 192-198; Jan 1987  
[Full Text]

Hemangioma Development in Transgenic Mice Carrying Polyoma Middle T-Antigen
Bautch V,
Hassell J,
Toda S,
Hanahan D

Journal of Cellular Biochemistry
  (0): 136-136; 1987  
[Full Text]

Transient Expression of an Insulin Gene Construct in Catecholaminergic Precursors of Transgenic Mouse Embryos
Alpert S,
Hanahan D,
Teitelman G

Society for Neuroscience Abstracts
  13 (1): 702; 1987  


Protein Expression in Pancreatic-Islets and B-Cell Tumors of Transgenic Mice
Baekkeskov S,
Hanahan D

Diabetologia
  29 (8): A514-A514; Aug 1986  
[Full Text]

Immunocytochemical and Ultrastructural-Study of Inherited Pancreatic Endocrine Tumors in Transgenic Mice
Power RF,
Holm R,
Bishop AE,
Varndell IM,
Hanahan D,
Alpert S,
Polak JM

Journal of Pathology
  149 (3): A251-A251; Jul 1986  
[Full Text]

Ultrastructural and Immunocytochemical Features of Heritable Pancreatic B-Cell Tumors Developed in Transgenic Mice and of Rat Islet Cell Tumor Lines
Varndell IM,
Polak JM,
Kalina M,
Hennessy RJ,
Holm R,
Alpert S,
Carrington CA,
Hanahan D,
Hales CN

Histochemical Journal
  18 (1): 57-58; Jan 1986  
[Full Text]

Bovine Papillomavirus Genome Elicits Skin Tumors in Transgenic Mice
Lacey M,
Alpert S,
Hanahan D

Nature (London)
  322 (6080): 609-612; 1986  
[Abstract]


Bidirectional Transcription and Developmental Regulation of the Rat Insulin Promoter Enhancer Region in Transgenic Mice
Hanahan D,
Alpert S,
Efrat S

Journal of Cellular Biochemistry
  (0): 91-91; 1986  
[Full Text]

Oncogenesis in Transgenic Mice
Hanahan D
In:
Oncogenes and Growth Control
(eds. Kahn, P. Graf, T.) Berlin; New York: Springer-Verlag; 1986. : 349-364  


Bidirectional Activity of the Rat Insulin-Ii Promoter Region in Transgenic Mice
Efrat S,
Alpert S,
Lacy M,
Hanahan D

Journal of Cellular Biochemistry
  (0): 55-55; 1986  
[Full Text]

Immunoelectron Microscopic Features of Pancreatic B-Cell Tumors Developed in Transgenic Mice and in Rat Islet Cell Tumor Lines
Varndell IM,
Polak JM,
Hennessy RJ,
Kalina M,
Alpert S,
Carrington CA,
Hanahan D,
Hales CN

Regulatory Peptides
  13 (1): 65-65; Dec 1985  
[Full Text]

Heritable Formation of Pancreatic Beta-Cell Tumors in Transgenic Mice Expressing Recombinant Insulin Simian Virus-40 Oncogenes
Hanahan D

Nature
  315 (6015): 115-122; 1985  
[Full Text]

Infection of Eukaryotic Cells by Helper-Independent Recombinant Adenoviruses - Early Region-1 Is Not Obligatory for Integration of Viral-DNA
Vandoren K,
Hanahan D,
Gluzman Y

Journal of Virology
  50 (2): 606-614; 1984  
[Full Text]

Rescue of Functional Replication Origins from Embedded Configurations in a Plasmid Carrying the Adenovirus Genome
Hanahan D,
Gluzman Y

Molecular Cellular Biology
  4 (2): 302-309; 1984  
[Abstract]


Oncogenes in Transgenic Mice
Hanahan D

Nature
  312 (5994): 503-504; 1984  
[Full Text]

Plasmid Screening at High Colony Density
Hanahan D,
Meselson M

Methods in Enzymology
  100 (0): 333-342; 1983  
[Full Text]

Studies on Transformation of Escherichia-Coli with Plasmids
Hanahan D

Journal of Molecular Biology
  166 (4): 557-580; 1983  
[Full Text]

Characteristics of an Sv40-Plasmid Recombinant and Its Movement into and out of the Genome of a Murine Cell
Hanahan D,
Lane D,
Lipsich L,
Wigler MH,
Botchan M

Cell
  21 (1): 127-139; Aug 1980  
[DOI] [Full Text]

Isolation of the chicken thymidine kinase gene by plasmid rescue
Perucho M,
Hanahan D,
Lipsich L,
Wigler MH

Nature
  285 (5762): 207-210; May 22 1980  
[Abstract]
[DOI] [Full Text]

DNA Mediated Gene Transfer: Theory and Application
Wigler MH,
Perucho M,
Lipsich L,
Lane D,
Klessig D,
Grodzicker T,
Botchan M,
Hanahan D

Journal of Supramolecular Structure
  9 (0): 229; 1980  


Genetic and Physical Linkage of Exogenous Sequences in Transformed-Cells
Perucho M,
Hanahan D,
Wigler MH

Cell
  22 (1): 309-317; 1980  
[Full Text]


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