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10 Article(s) on File
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A Computational Algorithm to Predict shRNA Potency
Knott SR,
Maceli AR,
Erard N,
Chang K,
Marran K,
Zhou X,
Gordon A,
El Demerdash O,
Wagenblast E,
Kim S,
Fellmann C,
Hannon GJ

Mol Cell
  (0): Nov 25 2014   Nlm
[Abstract]
[DOI] [Full Text]

Development of siRNA payloads to target KRAS-mutant cancer
Yuan TL,
Fellmann C,
Lee CS,
Ritchie CD,
Thapar V,
Lee LC,
Hsu DJ,
Grace D,
Carver JO,
Zuber J,
Luo J,
McCormick F,
Lowe SW

Cancer Discovery
  4 (10): 1182; Oct 1 2014   Nlm
[Abstract]
[DOI] [Full Text]

Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors
Lito P,
Saborowski A,
Yue J,
Solomon M,
Joseph E,
Gadal S,
Saborowski M,
Kastenhuber E,
Fellmann C,
Ohara K,
Morikami K,
Miura T,
Lukacs C,
Ishii N,
Lowe S,
Rosen N

Cancer Cell
  25 (5): 697-710; Apr 15 2014   NLM
[Abstract]
[DOI] [Full Text]

Next Generation RNAi Mouse Models for Drug Discovery and Toxicology Assessment
Premsrirut P,
Fellmann C,
Dow L,
Lowe S,
Zuber J,
Hannon G

European Journal of Cancer
  48 (0): 16-16; Nov 6 2012  
[Full Text]

Proffered Paper: Next Generation RNAi Mouse Models for Drug Discovery and Toxicology Assessment
Premsrirut P,
Fellmann C,
Hannon GJ,
Lowe SW,
Zuber J,
Elledge S

European Journal of Cancer
  48 (0): S14-S14; Jul 2012  
[Full Text]

A pipeline for the generation of shRNA transgenic mice
Dow LE,
Premsrirut PK,
Zuber J,
Fellmann C,
McJunkin K,
Miething C,
Park Y,
Dickins RA,
Hannon GJ,
Lowe SW

Nat Protoc
  7 (2): 374-93; Feb 2 2012   NLM
[Abstract]
[DOI] [Full Text]

Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy
Tan X,
Lu ZJ,
Gao G,
Xu QK,
Hu L,
Fellmann C,
Li MZ,
Qu HJ,
Lowe SW,
Hannon GJ,
Elledge SJ

Proceedings of the National Academy of Sciences of the United States of America
  109 (3): 869-874; Jan 2012  
[Abstract]
[DOI] [Full Text]

Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
Fellmann C,
Zuber J,
McJunkin K,
Chang K,
Malone CD,
Dickins R,
Xu Q,
Hengartner M,
Elledge SJ,
Hannon GJ,
Lowe SW

Molecular Cell
  41 (6): 733-746; Mar 18 2011   Array
[Abstract]
[DOI]

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
Zuber J,
McJunkin K,
Fellmann C,
Dow L,
Taylor MJ,
Hannon GJ,
Lowe SW

Nature Biotechnology
  29 (1): 79-85; Jan 2011  
[Abstract]
[DOI] [Full Text] [PDF]

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase
Sendoel A,
Kohler I,
Fellmann C,
Lowe SW,
Hengartner MO

Nature
  465 (7298): 577-U69; Jun 3 2010  
[Abstract]
[DOI] [Full Text] [PDF]


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