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11 Article(s) on File
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MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia
Chen C,
Liu Y,
Rappaport AR,
Kitzing T,
Schultz N,
Zhao Z,
Shroff AS,
Dickins RA,
Vakoc CR,
Bradner JE,
Stock W,
LeBeau MM,
Shannon KM,
Kogan S,
Zuber J,
Lowe SW

Cancer Cell
  25 (5): 652-65; May 1 2014   Nlm
[Abstract]
[DOI] [Full Text]

MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia
Chen C,
Liu Y,
Rappaport AR,
Kitzing T,
Schultz N,
Zhao Z,
Shroff AS,
Dickins RA,
Vakoc CR,
Bradner JE,
Stock W,
Lebeau MM,
Shannon KM,
Kogan S,
Zuber J,
Lowe SW

Cancer Cell
  25 (5): 652-665; Apr 30 2014   NLM
[Abstract]
[DOI] [Full Text]

A pipeline for the generation of shRNA transgenic mice
Dow LE,
Premsrirut PK,
Zuber J,
Fellmann C,
McJunkin K,
Miething C,
Park Y,
Dickins RA,
Hannon GJ,
Lowe SW

Nat Protoc
  7 (2): 374-93; Feb 2 2012   NLM
[Abstract]
[DOI] [Full Text]

A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference
Premsrirut PK,
Dow LE,
Kim SY,
Camiolo M,
Malone CD,
Miething C,
Scuoppo C,
Zuber J,
Dickins RA,
Kogan S,
Shroyer K,
Sordella R,
Hannon GJ,
Lowe SW

Cell
  145 (1): 145-158; Mar 31 2011   Elsevier
[Abstract]
[DOI]

Transgenic, inducible RNAi in megakaryocytes and platelets in mice
Takiguchi M,
James C,
Josefsson EC,
Carmichael CL,
Premsrirut PK,
Lowe SW,
Hamilton JR,
Huang DC,
Kile BT,
Dickins RA

J Thromb Haemost
  8 (12): 2751-6; Dec 2010  
[Abstract]
[DOI] [Full Text] [PDF]

Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence
Chicas A,
Wang X,
Zhang C,
McCurrach ME,
Zhao Z,
Mert O,
Dickins RA,
Narita M,
Zhang MQ,
Lowe SW

Cancer Cell
  17 (4): 376-387; Apr 12 2010   PMCID: PMC2889489
[Abstract]
[DOI] [Full Text] [PDF]

Tissue-specific and reversible RNA interference in transgenic mice
Dickins RA,
McJunkin K,
Hernando E,
Premsrirut PK,
Krizhanovsky V,
Burgess DJ,
Kim SY,
Cordon-Cardo C,
Zender L,
Hannon GJ,
Lowe SW

Nat Genet
  39 (7): 914 - 921; Jul 2007  
[Abstract]
[DOI] [Full Text] [PDF]

ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence
Ha L,
Ichikawa T,
Anver M,
Dickins RA,
Lowe SW,
Sharpless N,
Krimpenfort P,
DePinho RA,
Bennett DC,
Sviderskaya EV,
Merlino G

Proc Natl Acad Sci U S A
  104 (26): 10968-10973 ; Jun 26 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Xue W,
Zender L,
Miething C,
Dickins RA,
Hernando E,
Krizhanovsky V,
Cordon-Cardo C,
Lowe SW

Nature
  445 (7128): 656-660; Feb 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Tetracycline-regulated p53 knockdown in cells and transgenic mice
Dickins RA,
Premsrirut PK,
McJunkin K,
Kim SY,
Hannon GJ,
Lowe SW

Toxicologic Pathology
  34 (7): 1006-1006; 2006  
[Full Text]

Trp53 loss during in vitro selection contributes to acquired Ara-C resistance in acute myeloid leukemia
Yin B,
Kogan SC,
Dickins RA,
Lowe SW,
Largaespada DA

Experimental Hematology
  34 (5): 631-641; 2006  
[Abstract]
[DOI] [Full Text]


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