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138 Article(s) on File
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Role of the chromobox protein CBX7 in lymphomagenesis
Scott CL,
Gil J,
Hernando E,
Teruya-Feldstein J,
Narita M,
Martinez D,
Visakorpi T,
Mu D,
Cordon-Cardo C,
Peters G,
Beach D,
Lowe SW

Proc Natl Acad Sci U S A
  104 (13): 5389-94; Mar 27 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Cell biology - Risky immortalization by telomerase
Wang J,
Hannon GJ,
Beach DH

Nature
  405 (6788): 755-756; Jun 2000  
[Full Text]

Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model
Carnero A,
Hudson JD,
Hannon GJ,
Beach DH

Nucleic Acids Research
  28 (11): 2234-2241; Jun 2000  
[Abstract]
[Full Text]

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
Hammond SM,
Bernstein E,
Beach D,
Hannon GJ

Nature
  404 (6775): 293-296; Mar 2000  
[Abstract]
[Full Text]

A proinflammatory cytokine inhibits p53 tumor suppressor activity
Hudson JD,
Shoaibi MA,
Maestro R,
Carnero A,
Hannon GJ,
Beach DH

J Exp Med
  190 (10): 1375-82; Nov 15 1999   PMCID: PMC2195698
[Abstract]
[Full Text] [PDF]

Twist is a potential oncogene that inhibits apoptosis
Maestro R,
Dei Tos AP,
Hamamori Y,
Krasnokutsky S,
Sartorelli V,
Kedes L,
Doglioni C,
Beach DH,
Hannon GJ

Genes Dev
  13 (17): 2207-17; Sep 1 1999  
[Abstract]
[DOI] [Full Text] [PDF]

MaRX: an approach to genetics in mammalian cells
Hannon GJ,
Sun P,
Carnero A,
Xie LY,
Maestro R,
Conklin DS,
Beach D

Science
  283 (5405): 1129-30; Feb 19 1999  
[DOI] [Full Text]

p53-independent role of MDM2 in TGF-beta1 resistance
Sun P,
Dong P,
Dai K,
Hannon GJ,
Beach D

Science
  282 (5397): 2270-2; Dec 18 1998  
[Abstract]
[Full Text]

Myc activates telomerase
Wang J,
Xie LY,
Allan S,
Beach D,
Hannon GJ

Genes Dev
  12 (12): 1769-74; Jun 15 1998  
[Abstract]
[Full Text]

The Cdc2 protein kinase controls Cdc10/Sct1 complex formation
Connolly T,
Caligiuri M,
Beach D

Mol Biol Cell
  8 (6): 1105-15; Jun 1997  
[Abstract]
[Full Text]

Ran1 functions to control the Cdc10/Sct1 complex through Puc1
Caligiuri M,
Connolly T,
Beach D

Mol Biol Cell
  8 (6): 1117-28; Jun 1997  
[Abstract]
[Full Text]

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
Serrano M,
Lin AW,
McCurrach ME,
Beach D,
Lowe SW

Cell
  88 (5): 593-602; Mar 7 1997  
[Abstract]
[Full Text]

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
Alcorta DA,
Xiong Y,
Phelps D,
Hannon G,
Beach D,
Barrett JC

Proceedings of the National Academy of Sciences of the United States of America
  93 (24): 13742-13747; Nov 26 1996  
[Abstract]
[DOI] [Full Text]

p53-dependent association between cyclin G and the B subunit of protein phosphatase 2A
Okamoto K,
Kamibayashi C,
Serrano M,
Prives C,
Mumby MC,
Beach D

Mol Cell Biol
  16 (11): 6593-602; Nov 1996  
[Abstract]
[Full Text]

A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeast Schizosaccharomyces pombe
Casso D,
Beach D

Mol Gen Genet
  252 (5): 518-29; Oct 16 1996  
[Abstract]
[Full Text]

Cdc25 cell-cycle phosphatase as a target of c-myc
Galaktionov K,
Chen X,
Beach D

Nature
  382 (6591): 511-7; Aug 8 1996  
[Abstract]
[Full Text]

A connection between pre-mRNA splicing and the cell cycle in fission yeast: cdc28+ is allelic with prp8+ and encodes an RNA-dependent ATPase/helicase
Lundgren K,
Allan S,
Urushiyama S,
Tani T,
Ohshima Y,
Frendewey D,
Beach D

Mol Biol Cell
  7 (7): 1083-94; Jul 1996  
[Abstract]
[Full Text]

Role of the INK4a locus in tumor suppression and cell mortality
Serrano M,
Lee H,
Chin L,
Cordon-Cardo C,
Beach D,
DePinho RA

Cell
  85 (1): 27-37; Apr 5 1996  
[Abstract]
[Full Text]

Pub1 acts as an E6-AP-like protein ubiquitiin ligase in the degradation of cdc25
Nefsky B,
Beach D

Embo J
  15 (6): 1301-12; Mar 15 1996  
[Abstract]
[Full Text]

Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage
Li R,
Hannon GJ,
Beach D,
Stillman B

Curr Biol
  6 (2): 189-99; Feb 1 1996  
[Abstract]
[Full Text] [PDF]

Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines
Terry LA,
Boyd J,
Alcorta D,
Lyon T,
Solomon G,
Hannon G,
Berchuck A,
Beach D,
Barrett JC

Molecular Carcinogenesis
  16 (4): 221-228; 1996  
[Abstract]
[DOI] [Full Text]

Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2)
Demetrick DJ,
Zhang H,
Beach DH

Cytogenet Cell Genet
  73 (1): 104-7; 1996  
[Abstract]
[Full Text]

Chromosomal mapping of the human genes CKS1 to 8q21 and CKS2 to 9q22
Demetrick DJ,
Zhang H,
Beach DH

Cytogenet Cell Genet
  73 (3): 250-4; 1996  
[Abstract]
[Full Text]

Mutations and Altered Expression of P16(Ink4) in Human Cancer
Okamoto A,
Demetrick DJ,
Spillare EA,
Hagiwara K,
Hussain SP,
Bennett WP,
Forrester K,
Gerwin B,
Serrano M,
Beach DH,
Harris CC

Proceedings of the National Academy of Sciences of the United States of America
  91 (23): 11045-11049; Nov 1994  
[Abstract]
[DOI] [Full Text]

Frequent Deletion of Ink4a/Mts1 in Pediatric Acute Lymphoblastic-Leukemia
Okuda T,
Valentine MB,
Shurtleff SA,
Hulshof MG,
Komuro H,
Raimondi SC,
Pui CH,
Beach D,
Sherr CJ,
Look AT,
Downing JR

Blood
  84 (10): A298-A298; Nov 1994  


Cyclin G is a transcriptional target of the p53 tumor suppressor protein
Okamoto K,
Beach D

Embo J
  13 (20): 4816-22; Oct 17 1994  
[Abstract]
[Full Text]

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair
Li R,
Waga S,
Hannon GJ,
Beach D,
Stillman B

Nature
  371 (6497): 534-7; Oct 6 1994  
[Abstract]
[DOI] [Full Text] [PDF]

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
Hannon GJ,
Beach D

Nature
  371 (6494): 257-61; Sep 15 1994  
[Abstract]
[DOI] [Full Text]

p21-containing cyclin kinases exist in both active and inactive states
Zhang H,
Hannon GJ,
Beach D

Genes Dev
  8 (15): 1750-8; Aug 1 1994  
[Abstract]
[DOI] [Full Text]

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
Waga S,
Hannon GJ,
Beach D,
Stillman B

Nature
  369 (6481): 574-8; Jun 16 1994  
[Abstract]
[DOI] [Full Text] [PDF]

Repression of Cyclin D1 - a Novel Function of Myc
Philipp A,
Schneider A,
Vasrik I,
Finke K,
Xiong Y,
Beach D,
Alitalo K,
Eilers M

Molecular and Cellular Biology
  14 (6): 4032-4043; Jun 1994  
[Abstract]
[DOI] [Full Text] [PDF]

Construction of an improved host strain for two hybrid screening
Feilotter HE,
Hannon GJ,
Ruddell CJ,
Beach D

Nucleic Acids Res
  22 (8): 1502-3; Apr 25 1994  
[DOI] [Full Text]

KAP: a dual specificity phosphatase that interacts with cyclin-dependent kinases
Hannon GJ,
Casso D,
Beach D

Proc Natl Acad Sci U S A
  91 (5): 1731-5; Mar 1 1994  
[Abstract]
[Full Text]

P16(Ink4) - an Specific Inhibitor of the Cdk4/Cyclin-D Kinase
Beach D,
Serrano M,
Hannon GJ

Journal of Cellular Biochemistry
  (0): 161-161; Feb 1994  


cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis
Hofmann JF,
Beach D

Embo J
  13 (2): 425-34; Jan 15 1994  
[Abstract]
[Full Text]

Interaction between the Cig1 and Cig2 B-type cyclins in the fission yeast cell cycle
Connolly T,
Beach D

Mol Cell Biol
  14 (1): 768-76; Jan 1994  
[Abstract]
[DOI] [Full Text]

Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes
Demetrick DJ,
Zhang H,
Beach DH

Cytogenet Cell Genet
  66 (1): 72-4; 1994  
[Abstract]
[Full Text]

p21 is a component of active cell cycle kinases
Zhang H,
Hannon GJ,
Casso D,
Beach D

Cold Spring Harb Symp Quant Biol
  59 (0): 21-9; 1994  
[DOI] [Full Text]

p21 is a universal inhibitor of cyclin kinases
Xiong Y,
Hannon GJ,
Zhang H,
Casso D,
Kobayashi R,
Beach D

Nature
  366 (6456): 701-4; Dec 16 1993  
[Abstract]


A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
Serrano M,
Hannon GJ,
Beach D

Nature
  366 (6456): 704-7; Dec 16 1993  
[Abstract]


Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins
Hannon GJ,
Demetrick D,
Beach D

Genes Dev
  7 (12): 2378-91; Dec 1993  
[Abstract]


Chromosome mapping of human CDC25A and CDC25B phosphatases
Demetrick DJ,
Beach DH

Genomics
  18 (1): 144-7; Oct 1993  
[Abstract]


Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes
Zhang H,
Xiong Y,
Beach D

Mol Biol Cell
  4 (9): 897-906; Sep 1993  
[Abstract]


Proliferating Cell Nuclear Antigen and P21 Are Components of Multiple Cell-Cycle Kinase Complexes
Hui Z,
Yue X,
Beach D

Molecular Biology of the Cell
  4 (9): 897-906; Sep 1993  
[Abstract]
[Full Text]

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation
Xiong Y,
Zhang H,
Beach D

Genes Dev
  7 (8): 1572-83; Aug 1993  
[Abstract]


Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2
Walworth N,
Davey S,
Beach D

Nature
  363 (6427): 368-71; May 27 1993  
[Abstract]


Identification of 7 New Cut Genes Involved in Schizosaccharomyces-Pombe Mitosis
Samejima I,
Matsumoto T,
Nakaseko Y,
Beach D,
Yanagida M

Journal of Cell Science
  105 (0): 135-143; May 1993  
[Abstract]
[Full Text]

2 New Multipurpose Multicopy Schizosaccharomyces-Pombe Shuttle Vectors, Psp1 and Psp2
Cottarel G,
Beach D,
Deuschle U

Current Genetics
  23 (5): 547-548; May-Jun 1993  
[Abstract]
[Full Text]

Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity
Molz L,
Beach D

Embo J
  12 (4): 1723-32; Apr 1993  
[Abstract]


A 13-Kb Resolution Cosmid Map of the 14-Mb Fission Yeast Genome by Nonrandom Sequence-Tagged Site Mapping
Mizukami T,
Chang WI,
Garkavtsev I,
Kaplan N,
Lombardi D,
Matsumoto T,
Niwa O,
Kounosu A,
Yanagida M,
Marr TG,
Beach D

Cell
  73 (1): 121-132; Apr 1993  
[Abstract]
[Full Text]

Interaction of the pim1/spi1 mitotic checkpoint with a protein phosphatase
Matsumoto T,
Beach D

Mol Biol Cell
  4 (3): 337-45; Mar 1993  
[Abstract]


Sct1 functions in partnership with Cdc10 in a transcription complex that activates cell cycle START and inhibits differentiation
Caligiuri M,
Beach D

Cell
  72 (4): 607-19; Feb 26 1993  
[Abstract]


D-Type Cyclins Associate with Multiple Protein-Kinases and the DNA-Replication and Repair Factor Pcna
Xiong Y,
Zhang H,
Beach D

Cell
  71 (3): 505-514; Oct 1992  
[Abstract]
[Full Text]

Growth-Regulated Expression of D-Type Cyclin Genes in Human-Diploid Fibroblasts
Won KA,
Xiong Y,
Beach D,
Gilman MZ

Proceedings of the National Academy of Sciences of the United States of America
  89 (20): 9910-9914; Oct 1992  
[Abstract]
[Full Text]

Molecular-Cloning and Chromosomal Mapping of Ccnd Genes Encoding Human D-Type Cyclins
Xiong Y,
Menninger J,
Beach D,
Ward DC

Genomics
  13 (3): 575-584; Jul 1992  
[Full Text]

Screening for Antimitotic Compounds Using the Cdc25 Tyrosine Phosphatase, and Activator of the Mitosis-Inducing P34(Cdc2) Cyclin-B(Cdc13) Protein-Kinase
Baratte B,
Meijer L,
Galaktionov K,
Beach D

Anticancer Research
  12 (3): 873-880; May-Jun 1992  
[Abstract]
[Full Text]

Human p53 inhibits growth in Schizosaccharomyces pombe
Bischoff JR,
Casso D,
Beach D

Mol Cell Biol
  12 (4): 1405-11; Apr 1992  
[Abstract]
[Full Text]

Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B
Jessus C,
Beach D

Cell
  68 (2): 323-32; Jan 24 1992  
[Abstract]
[DOI] [Full Text]

Regulation of the Eukaryotic Cell-Cycle - Final Discussion
Yanagida ,
Wang ,
Hunter ,
Morris ,
Sherr ,
Stillman ,
Cross ,
Kirschner ,
Beach ,
Hunt

Ciba Foundation Symposia
  170 (0): 276-278; 1992  
[Full Text]

The Role of Mos in Meiotic Maturation
Woude V,
Hunt ,
Hunter ,
Doree ,
Kirschner ,
Shalloway ,
Nasmyth ,
Beach ,
Cross ,
Nigg

Ciba Foundation Symposia
  170 (0): 244-247; 1992  
[Full Text]

The Cyclin-Dependent Kinase Family
Harlow ,
Hunter ,
Nasmyth ,
Hunt ,
Kirschner ,
Beach ,
Pines ,
Reed ,
Yanagida ,
Lehner

Ciba Foundation Symposia
  170 (0): 205-208; 1992  
[Full Text]

Cell-Cycle Control
Beach D

Faseb Journal
  6 (1): A126-A126; Jan 1992  
[Full Text]

Genetic Dissection of Cell-Cycle Dependency
Beach D

Harvey Lectures
  86 (0): 19-31; 1992  
[Full Text]

Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins
Galaktionov K,
Beach D

Cell
  67 (6): 1181-94; Dec 20 1991  
[Abstract]
[Full Text]

Population explosion in the cyclin family
Xiong Y,
Beach D

Curr Biol
  1 (6): 362-4; Dec 1991  
[Full Text]

P34cdc2-Mediated Phosphorylation at T124 Inhibits Nuclear Import of Sv40 T-Antigen Proteins
Jans DA,
Ackermann MJ,
Bischoff JR,
Beach DH,
Peters R

Journal of Cell Biology
  115 (5): 1203-1212; Dec 1991  
[Abstract]
[Full Text]

Interaction between ran1+ protein kinase and cAMP dependent protein kinase as negative regulators of fission yeast meiosis
DeVoti J,
Seydoux G,
Beach D,
McLeod M

Embo J
  10 (12): 3759-68; Dec 1991  
[Abstract]
[Full Text]

Cell cycle regulation of histone H1 kinase activity associated with the adenoviral protein E1A
Giordano A,
Lee JH,
Scheppler JA,
Herrmann C,
Harlow E,
Deuschle U,
Beach D,
Franza BR

Science
  253 (5025): 1271-5; Sep 13 1991  
[Abstract]
[Full Text]

A Cdc2-Like Kinase Phosphorylates Histone-H1 in the Amitotic Macronucleus of Tetrahymena
Roth SY,
Collini MP,
Draetta G,
Beach D,
Allis CD

Embo Journal
  10 (8): 2069-2075; Aug 1991  
[Abstract]
[Full Text]

Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase
Matsumoto T,
Beach D

Cell
  66 (2): 347-60; Jul 26 1991  
[Abstract]
[Full Text]

Human D-type cyclin
Xiong Y,
Connolly T,
Futcher B,
Beach D

Cell
  65 (4): 691-9; May 17 1991  
[Abstract]
[Full Text]

A Role for the P34cdc2 Kinase and Phosphatases in the Regulation of Phosphorylation and Disassembly of Lamin-B2 During the Cell-Cycle
Luscher B,
Brizuela L,
Beach D,
Eisenman RN

Embo Journal
  10 (4): 865-875; Apr 1991  
[Abstract]
[Full Text]

mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2
Lundgren K,
Walworth N,
Booher R,
Dembski M,
Kirschner M,
Beach D

Cell
  64 (6): 1111-22; Mar 22 1991  
[Abstract]
[Full Text]

A Complex Containing P34cdc2 and Cyclin-B Phosphorylates the Nuclear Lamin and Disassembles Nuclei of Clam Oocytes Invitro
Dessev G,
Iovchevadessev C,
Bischoff JR,
Beach D,
Goldman R

Journal of Cell Biology
  112 (4): 523-533; Feb 1991  
[Abstract]
[Full Text]

The spil GTPase interacts with RCCl in cell cycle dependency
Matsumoto T,
Beach D

Cold Spring Harb Symp Quant Biol
  56 (0): 385-98; 1991  
[Full Text]

Spi1 GTPase interacts with RCC1 to maintain interdependency of cell cycle events
Matsumoto T,
Beach D

Princess Takamatsu Symp
  22 (0): 145-52; 1991  
[Abstract]
[Full Text]

Mik1 and Wee1 Mitotic Inhibitors Cooperate in Cdc2 Tyrosine Phosphorylation
Lundgren K,
Beach D

Journal of Cell Biology
  115 (3): 423A; 1991  


Human Homolog of the Fission Yeast Cdc25 Gene Is Essential for Mitosis
Galaktionov K,
Beach D

Journal of Cell Biology
  115 (3): 424A; 1991  


Fission Yeast Cyclins
Connolly T,
Molz L,
Futcher B,
Beach D

Journal of Cellular Biochemistry - Supplement.(15 PART B)
  (0): 92; 1991  


A Yeast System to Study Human P53
Bischoff JR,
Casso D,
Beach D
In:
Origins of human cancer: a comprehensive review
(eds. Brugge, J. et al.) Plainview, N. Y.: Cold Spring Harbor L; 1991. : 51-63  


Expression of Human P53 in Fission Yeast
Bischoff JR,
Casso D,
Beach D

Journal of Cellular Biochemistry - Supplement
  15 (0): 65; 1991  


Cold Spring Harbor Symposia on Quantitative Biology - Foreword
Beach D,
Stillman B,
Watson JD

Cold Spring Harbor Symposia on Quantitative Biology LVI: The Cell Cycle
  56 R21-R22; 1991  


Distinct Nuclear and Spindle Pole Body Populations of Cyclin-Cdc2 in Fission Yeast
Alfa CE,
Ducommun B,
Beach D,
Hyams JS

Nature
  347 (6294): 680-682; Oct 1990  
[Full Text]

Intermediate Filament Reorganization During Mitosis Is Mediated by P34cdc2 Phosphorylation of Vimentin
Chou YH,
Bischoff JR,
Beach D,
Goldman RD

Cell
  62 (6): 1063-1071; Sep 1990  
[Full Text]

Cell cycle regulation of p34cdc2 kinase activity in Physarum polycephalum
Ducommun B,
Tollon Y,
Gares M,
Beach D,
Wright M

J Cell Sci
  96 ( (0): 683-9; Aug 1990  
[Abstract]
[Full Text] [PDF]

Direct activation of cdc2 with phosphatase: identification of p13suc1-sensitive and insensitive steps
Jessus C,
Ducommun B,
Beach D

FEBS Lett
  266 (1): 4-8; Jun 18 1990  
[Abstract]
[Full Text]

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2
Bischoff JR,
Friedman PN,
Marshak DR,
Prives C,
Beach D

Proc Natl Acad Sci U S A
  87 (12): 4766-70; Jun 1990  
[Abstract]
[Full Text]

A versatile microtiter assay for the universal cdc2 cell cycle regulator
Ducommun B,
Beach D

Anal Biochem
  187 (1): 94-7; May 15 1990  
[Abstract]
[DOI] [Full Text]

Fission yeast cdc25 is a cell-cycle regulated protein
Ducommun B,
Draetta G,
Young P,
Beach D

Biochem Biophys Res Commun
  167 (1): 301-9; Feb 28 1990  
[Abstract]
[Full Text]

Activation of M-Phase-Specific Histone H1 Kinase by Modification of the Phosphorylation of Its P34cdc2 and Cyclin Components
Pondaven P,
Meijer L,
Beach D

Genes Development
  4 (1): 9-17; Jan 1990  
[Full Text]

Identification and Characterization of a Novel Mitotic Inhibitory Kinase in Schizosaccharomyces-Pombe
Lundgren K,
Dembski M,
Beach D

Journal of Cell Biology
  111 (5): 93A; 1990  


Regulation of the Cell Cycle by Cdc2 and Its Associated Cyclins
Beach D,
Draetta G

Journal of Cellular Biochemistry - Supplement.(14 PART E)
  (0): 132; 1990  


Genetic dissection of cell cycle dependency
Beach D

Harvey Lect
  86 (0): 19-31; 1990  
[Full Text]

Phosphorylation of large tumour antigen by cdc2 stimulates SV40 DNA replication
McVey D,
Brizuela L,
Mohr I,
Marshak DR,
Gluzman Y,
Beach D

Nature
  341 (6242): 503-7; Oct 12 1989  
[Abstract]
[Full Text]

A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells
Giordano A,
Whyte P,
Harlow E,
Franza BR,
Beach D,
Draetta G

Cell
  58 (5): 981-90; Sep 8 1989  
[Abstract]
[Full Text]

The fission yeast cdc2/cdc13/suc1 protein kinase: regulation of catalytic activity and nuclear localization
Booher RN,
Alfa CE,
Hyams JS,
Beach DH

Cell
  58 (3): 485-97; Aug 11 1989  
[Abstract]
[Full Text]

cdc2 and the regulation of mitosis: six interacting mcs genes
Molz L,
Booher R,
Young P,
Beach D

Genetics
  122 (4): 773-82; Aug 1989  
[Abstract]
[Full Text]

Cyclin Is a Component of the Sea-Urchin Egg M-Phase Specific Histone H-1 Kinase
Meijer L,
Arion D,
Golsteyn R,
Pines J,
Brizuela L,
Hunt T,
Beach D

Embo Journal
  8 (8): 2275-2282; Aug 1989  
[Full Text]

Reversible Tyrosine Phosphorylation of Cdc2 - Dephosphorylation Accompanies Activation During Entry into Mitosis
Morla AO,
Draetta G,
Beach D,
Wang JY

Cell
  58 (1): 193-203; Jul 1989  
[Full Text]

Involvement of a type 1 protein phosphatase encoded by bws1+ in fission yeast mitotic control
Booher R,
Beach D

Cell
  57 (6): 1009-16; Jun 16 1989  
[Abstract]
[Full Text]

Activation of human CDC2 protein as a histone H1 kinase is associated with complex formation with the p62 subunit
Brizuela L,
Draetta G,
Beach D

Proc Natl Acad Sci U S A
  86 (12): 4362-6; Jun 1989  
[Abstract]
[Full Text]

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells
Riabowol K,
Draetta G,
Brizuela L,
Vandre D,
Beach D

Cell
  57 (3): 393-401; May 5 1989  
[Abstract]
[Full Text]

Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF
Draetta G,
Luca F,
Westendorf J,
Brizuela L,
Ruderman J,
Beach D

Cell
  56 (5): 829-38; Mar 10 1989  
[Abstract]
[Full Text]

The mammalian cdc2 protein kinase: mechanisms of regulation during the cell cycle
Draetta G,
Beach D

J Cell Sci Suppl
  12 (0): 21-7; 1989  
[Abstract]
[Full Text]

Fission Yeast Cyclin - Subcellular-Localization and Cell-Cycle Regulation
Alfa CE,
Booher R,
Beach D,
Hyams JS

Journal of Cell Science
  (0): 9-19; 1989  
[Full Text]

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate
Draetta G,
Piwnica-Worms H,
Morrison D,
Druker B,
Roberts T,
Beach D

Nature
  336 (6201): 738-44; Dec 22 1988  
[Abstract]
[Full Text]

Cdc2 Is a Component of the M-Phase Specific Histone-H1 Kinase - Evidence for Identity with Mpf
Arion D,
Meijer L,
Brizuela L,
Beach D

Cell
  55 (2): 371-378; Oct 1988  
[Full Text]

Cyclin in Fission Yeast
Solomon M,
Booher R,
Kirschner M,
Beach D

Cell
  54 (6): 738-739; Sep 1988  
[Full Text]

Multiple phosphorylated forms of the product of the fission yeast cell division cycle gene cdc2+
Potashkin JA,
Beach DH

Curr Genet
  14 (3): 235-40; Sep 1988  
[Abstract]
[Full Text]

Involvement of cdc13+ in mitotic control in Schizosaccharomyces pombe: possible interaction of the gene product with microtubules
Booher R,
Beach D

Embo J
  7 (8): 2321-7; Aug 1988  
[Abstract]
[Full Text]

The Xenopus Cdc2 Protein Is a Component of Mpf, a Cytoplasmic Regulator of Mitosis
Dunphy WG,
Brizuela L,
Beach D,
Newport J

Cell
  54 (3): 423-431; Jul 1988  
[Full Text]

Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement
Draetta G,
Beach D

Cell
  54 (1): 17-26; Jul 1 1988  
[Abstract]
[Full Text]

Synthesis of p34, the mammalian homolog of the yeast cdc2+/CDC28 protein kinase, is stimulated during adenovirus-induced proliferation of primary baby rat kidney cells
Draetta G,
Beach D,
Moran E

Oncogene
  2 (6): 553-7; Jun 1988  
[Abstract]
[Full Text]

Four mating-type genes control sexual differentiation in the fission yeast
Kelly M,
Burke J,
Smith M,
Klar A,
Beach D

Embo J
  7 (5): 1537-47; May 1988  
[Abstract]
[Full Text]

A specific inhibitor of the ran1+ protein kinase regulates entry into meiosis in Schizosaccharomyces pombe
McLeod M,
Beach D

Nature
  332 (6164): 509-14; Apr 7 1988  
[Abstract]
[Full Text]

Regulation of the vertebrate cell cycle by the cdc2 protein kinase
Draetta G,
Brizuela L,
Moran B,
Beach D

Cold Spring Harb Symp Quant Biol
  53 Pt (0): 195-201; 1988  
[Full Text]

p34, a protein kinase involved in cell cycle regulation in eukaryotic cells
Draetta G,
Brizuela L,
Beach D

Adv Exp Med Biol
  231 (0): 453-7; 1988  
[Full Text]

P34 Protein Kinase a Human Homolog of the Yeast Cell Cycle Control Proteins Encoded by Cdc2+ and Cdc28
Draetta G,
Brizuela L,
Beach D
In:
Eukaryotic DNA replication
(eds. Kelly, T. Stillman, B.) Cold Spring Harbor, NY: Cold Spring Harbor L; 1988. 6: 259-264  


Human Homolog of the Yeast Cdc2-Positive-Cdc28 Cell-Cycle Regulator Cyclic Activation of the Protein Kinase During Mitosis
Draetta G,
Beach D
In:
Cell Cycle Control in Eukaryotes;
(eds. Beach, D. Basilico, C. Newport, J.) Cold Spring Harbor, NY: Cold Spring Harbor L; 1988. : 113-117  


Involvement of Cyclin Cdc13 in Miotic Control in Fission Yeast
Beach D,
Alfa C,
Hyams J,
Booher R

Journal of Cell Biology
  107 (6): 664A; 1988  


p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase
Brizuela L,
Draetta G,
Beach D

Embo J
  6 (11): 3507-14; Nov 1987  
[Abstract]
[Full Text]

Interaction between cdc13+ and cdc2+ in the control of mitosis in fission yeast; dissociation of the G1 and G2 roles of the cdc2+ protein kinase
Booher R,
Beach D

Embo J
  6 (11): 3441-7; Nov 1987  
[Abstract]
[Full Text]

Identification of P34 and P13, Human Homologs of the Cell-Cycle Regulators of Fission Yeast Encoded by Cdc2+ and Suc1+
Draetta G,
Brizuela L,
Potashkin J,
Beach D

Cell
  50 (2): 319-325; Jul 1987  
[Full Text]

Physical Association between Products of Cdc2-Positive and Sucl-Positive Genes of Fission Yeast and between Their Homologs in Mammalian Cells
Brizuela L,
Draetta G,
Potashkin J,
Beach D
In:
Nuclear Oncogenes
(eds. Alt, F. W. Harlow, E. Ziff, E. B) Cold Spring Harbor, NY: Cold Spring Harbor L; 1987. : 38-42  


The Product of the Mei-3+ Gene Expressed under Control of the Mating-Type Locus Induces Meiosis and Sporulation in Fission Yeast
McLeod M,
Stein M,
Beach D

EMBO (European Molecular Biology Organization) Journal
  6 (3): 729-736; 1987  
[Abstract]
[Full Text]

Sucl+ Encodes a Predicted 13-Kilodalton Protein That Is Essential for Cell Viability and Is Directly Involved in the Division Cycle of Schizosaccharomyces-Pombe
Hindley J,
Phear G,
Stein M,
Beach D

Molecular and Cellular Biology
  7 (1): 504-511; Jan 1987  
[Full Text]

Isolation of Temperature Sensitive Cdc-13 Mutation That Suppresses a Cold-Sensitive Allele of the Cdc-2 Protein Kinase in Schizosaccharomyces-Pombe
Booher R,
Beach D

Genetics
  116 (1): S25; 1987  


Homology between the Ran1+ Gene of Fission Yeast and Protein-Kinases
McLeod M,
Beach D

Embo Journal
  5 (13): 3665-3671; Dec 1986  
[Full Text]

Involvement of Ras in Sexual-Differentiation but Not in Growth-Control in Fission Yeast
Nadindavis SA,
Nasim A,
Beach D

Embo Journal
  5 (11): 2963-2971; Nov 1986  
[Full Text]

Site-Specific Mutagenesis of Cdc2+, a Cell-Cycle Control Gene of the Fission Yeast Schizosaccharomyces-Pombe
Booher R,
Beach D

Molecular and Cellular Biology
  6 (10): 3523-3530; Oct 1986  
[Full Text]

Fission Yeast Enters the Stationary Phase G0 State from Either Mitotic G1 or G2
Costello G,
Rodgers L,
Beach D

Current Genetics
  11 (2): 119-125; 1986  
[Full Text]

ran1+ controls the transition from mitotic division to meiosis in fission yeast
Beach D,
Rodgers L,
Gould J

Curr Genet
  10 (4): 297-311; 1985  
[Abstract]
[Full Text]

Sexual Differentiation Is Controlled by a Protein Kinase Encoded by the Ran-1-Positive Gene in Fission Yeast
Beach D

Cold Spring Harbor Symposia on Quantitative Biology L: Molecular Biology of Development
  50 635-641; 1985  


Genes Required for Initiation and Resolution Steps of Mating-Type Switching in Fission Yeast
Egel R,
Beach DH,
Klar AJ

Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences
  81 (11): 3481-3485; 1984  
[Full Text]

Rearrangements of the Transposable Mating-Type Cassettes of Fission Yeast
Beach DH,
Klar AJ

Embo Journal
  3 (3): 603-610; 1984  
[Full Text]

Cell Type Switching by DNA Transposition in Fission Yeast
Beach DH

Nature (London)
  305 (5936): 682-688; 1983  
[Abstract]


Structure of the Mating Type Locus in Schizosaccharomyces-Pombe
Beach D,
Klar A

Journal of Cellular Biochemistry - Supplement.(7 PART B)
  (0): 143; 1983  


Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts
Won K,
Xiong Y,
Beach D,
Gilman MZ

Proceedings of the National Academy of Sciences of the United States of America
  89 (20): 9910-9914; 1972  
[Abstract]
[Full Text]


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