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The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy
Ellis L,
Bots M,
Lindemann RK,
Bolden JE,
Newbold A,
Cluse LA,
Scott CL,
Strasser A,
Atadja P,
Lowe SW,
Johnstone RW

Blood
  114 (2): 380-393; Jul 9 2009  
[Abstract]
[DOI] [Full Text] [PDF]

Characterization of the apoptotic and therapeutic activities of the histone deacetylase inhibitors LAQ824 and LBH589 using a mouse model of B cell lymphoma
Ellis L,
Lindemann R,
Newbold A,
Whitecross K,
Cluse L,
Pelligrini M,
Wei A,
Scott C,
Atadja P,
Lowe SW,
Johnstone RW

Molecular Cancer Therapeutics
  6 (12): 3475S-3476S; Dec 2007  
[Full Text]


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